%0 English Abstract
%T [The measuring of ECP and IgE in middle ear effusion of patients with otitis media of effusion].
%A Tian J
%A Lu H
%A Liu Y
%A Sun C
%A Xue H
%A Meng W
%A Liu H
%J Lin Chuang Er Bi Yan Hou Ke Za Zhi
%V 20
%N 10
%D May 2006
%M 16883790
暂无%X <B>OBJECTIVE: </B>To study the relationship between otitis media of effusion (OME) and allergy by investigating eosinophil cationic protein in middle ear effusion ( MECP), middle ear effusion IgE (MIgE) and serum eosinophil cationic protein (SECP).<BR><B>METHODS: </B>The specimens drawn from 31 patients of OME were tested with Uni-CAP-100 allergic antigen testing system for the MECP, IgE and SECP. The results then were analyzed by statistical methods.<BR><B>RESULTS: </B>MECP were found in all the effusion specimens of 31 patients, the average concentration of which was 56.88 microg/L. The MECP concentration level in nine specimens (28.1%) was significantly elevated. The average concentration of MIgE was 27.2 ku/L. The MIgE concentration level in three specimens (9.7%) was remarkably increased. There was a positive correlation between the MECP level and the MIgE level( P <0.05). The average concentration of SECP was 5.6 microg/L.<BR><B>CONCLUSIONS: </B>ECP exists in the middle ear effusion of OME. OME is an allergic inflammatory process more localized in middle ear itself in some patients. There may be a complicated allergic mechanism in OME.