%0 Journal Article
%T Pressure as a tool to study protein-unfolding/refolding processes: the case of ribonuclease A.
%A Ribó M
%A Font J
%A Benito A
%A Torrent J
%A Lange R
%A Vilanova M
%J Biochim Biophys Acta
%V 1764
%N 3
%D Mar 2006
%M 16388998
暂无%R 10.1016/j.bbapap.2005.11.011
%X This paper gives an overview of the application of high-pressure to study the folding/unfolding processes of proteins using Ribonuclease A as a model protein. A particular focus is the study of pressure-equilibrium unfolding and folding kinetics using variants and the information obtained by comparing these with the wild-type enzyme.