%0 Journal Article
%T Dealing with Depo: you can manage bleeding with estrogen, ibuprofen.
%J Contracept Technol Update
%V 16
%N 12
%D Dec 1995
%M 12347032
暂无%X Irregular menstrual bleeding, the most common side effect of Depo-Provera use, is being managed by some physicians through administration of estrogen and/or ibuprofen.  A practitioner from the Jones Institute for Reproductive Medicine in Norfolk, Virginia, reported that women with 8-10 days of bleeding over 2 weeks are administered 0.02 mg of ethinyl estradiol for 10 days; bleeding generally stops in 5 days.  Other physicians prescribe an estrogen patch.  If estrogen is contraindicated, patients are given 800 mg of ibuprofen 3 times a day for 5 days.  In all cases of heavy bleeding apparently related to Depo-Provera use, other causes (e.g., cervical malignancy, uterine fibroids, sexually transmitted diseases) should be ruled out before treatment is initiated.  Finally, several clinicians noted that counseling Depo-Provera acceptors to anticipate irregular bleeding for as long as a year is perhaps the most effective management strategy.