Mesh : Acute Kidney Injury / chemically induced Analgesics, Non-Narcotic / administration & dosage adverse effects Fundoplication Gastroesophageal Reflux / surgery Humans Injections, Intramuscular Ionophores Ketorolac Tromethamine Male Middle Aged Postoperative Complications / chemically induced Tolmetin / administration & dosage adverse effects analogs & derivatives Tromethamine / adverse effects analogs & derivatives

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Abstract:
The nephrotoxic effects of nonsteroidal anti-inflammatory drugs (NSAIDs) are well recognized. Known potentiating risk factors include pre-existing renal disease, intravascular volume depletion, and concomitant administration of other nephrotoxic drugs. We present a case report of renal failure following short term usage of intramuscular ketorolac (Toradol) in a patient with no known risk factors who underwent an uncomplicated laparotomy. The literature concerning ketorolac-induced renal failure is reviewed and physicians are reminded to be aware of this potential complication.
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