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Abstract：
Anatomico-pathological and radiological studies of osteopoikilosis were performed in two cases, one involving a femoral head, excised after a fracture of a femoral neck, in an elderly man and the other following biopsy of an iliac crest in a young woman. In both patients wide-spread radiological evidence of the disorder was present as an incidental finding. The radiological appearance of rounded and linear densities corresponded to old and inactive remodelling of spongy trabeculae in epiphyseal and metaphyseal locations. The distribution and appearance of these osteopoikilotic densities suggested them to have been related intimately to mechanical strain on spongy bone trabeculae. The diffuse nature of the lesions, their hereditary character, and their possible association with abnormalities of the skin suggest the existence of a particular terrain in which general metabolic conditions of connective tissue may interact with mechanical stresses in bone. Careful analysis of the findings in osteopoikilosis is desirable in order to provide data concerning the physiopathology of the skeleton and to permit more definitive interpretation of localised areas of bone condensation, including those observed not only in solitary bone islands and such conditions as osteopathia striata, but also those associated with infections and tumours.
摘要：
对2例患者进行了骨质疏松的解剖学病理学和放射学研究，一个涉及股骨头，在股骨颈骨折后切除，一名老年男子和一名年轻女子髂棘活检后的另一名男子。在这两名患者中，偶然发现了广泛的放射学证据。圆形和线性密度的放射学外观对应于the骨和干phy端位置的海绵状小梁的旧而无活性重塑。这些骨质疏松密度的分布和出现表明它们与海绵状骨小梁的机械应变密切相关。病变的弥漫性,他们的遗传特征，它们可能与皮肤异常有关，这表明存在特定的地形，在该地形中，结缔组织的一般代谢状况可能与骨骼中的机械应力相互作用。为了提供有关骨骼病理生理学的数据，并允许对骨凝结的局部区域进行更明确的解释，需要仔细分析骨质疏松的发现。包括那些不仅在孤立的骨岛和骨病变等条件下观察到的，还有那些与感染和肿瘤有关的。
