Abstract：
To demonstrate the burden of sexual dysfunction (SD) among females with rheumatic diseases, we conducted a cross-sectional comparative study in patients with systemic sclerosis (SSc), systemic lupus erythematosus (SLE), and Behçet\'s syndrome (BS) along with suitable healthy controls (HCs). Age-matched female patients with SSc (n = 50), SLE (n = 49), and BS (n = 54), along with 52 female HCs were included in this study between April and October, 2021. Sociodemographic features were recorded, and psychometric tests, i.e., female sexual function index (FSFI), Beck depression inventory (BDI), body cathexis scale, and marital adjustment test (MAT) were performed. Scale scores were compared, and binary logistic regression was used to identify predictors for SD in the whole group. The total FSFI and body cathexis scores among the patient groups were significantly lower than those of the HCs (p < 0.001). Depression was significantly more frequent in the patient groups. MAT scores did not differ significantly between the study groups. Patients with SSc had the worst scores in each psychometric index, including MAT. Decreased body cathexis score [OR 0.974, 95% CI (0.957-0.991), p = 0.003] and low MAT score [OR 0.937, 95% CI (0.896-0.980), p = 0.005], and being diagnosed with SSc [OR 6.6, 95% CI (1.975-22.498), p = 0.002], SLE [OR 2.7, 95% CI (0.998-7.753), p = 0.050], and BS [OR 2.8, 95% CI (1.100-7.359), p = 0.031], were identified as independent predictors for SD. Body cathexis seems to be the most important independent predictor for SD, and the burden of SD appears heavier in patients with SSc, probably due to poor body image satisfaction.
摘要：
为了证明风湿性疾病女性的性功能障碍（SD）负担，我们在系统性硬化症（SSc）患者中进行了横断面比较研究，系统性红斑狼疮（SLE），和Behçet综合征（BS）以及合适的健康对照（HC）。年龄匹配的女性SSc患者（n=50），SLE（n=49），和BS（n=54），在4月至10月期间，该研究包括52名女性HCs，2021年。记录了社会人口学特征，和心理测试，即，女性性功能指数（FSFI），贝克抑郁库存(BDI)，身体导管刻度，进行婚姻调整测试（MAT）。比较量表得分，并使用二元逻辑回归来确定整个组中SD的预测因子。患者组的总FSFI和身体导管评分明显低于HC（p<0.001）。抑郁症在患者组中明显更常见。研究组之间的MAT评分没有显着差异。SSc患者在每个心理测量指数中得分最差，包括MAT。身体导管评分降低[OR0.974，95%CI（0.957-0.991），p=0.003]和低MAT评分[OR0.937，95%CI（0.896-0.980），p=0.005],并被诊断为SSc[OR6.6，95%CI（1.975-22.498），p=0.002],SLE[OR2.7，95%CI（0.998-7.753），p=0.050],和BS[OR2.8，95%CI（1.100-7.359），p=0.031],被确定为SD的独立预测因子。身体导管似乎是SD最重要的独立预测因子，SSc患者的SD负担似乎更重，可能是由于身体形象满意度差。
