Abstract：
Background Rosacea is a chronic inflammatory disease of the skin characterised by facial erythema, oedema, telangiectasias, papules, pustules and nodules. There is a paucity of effective therapeutic modalities for the management of rosacea. Intense Pulsed Light (IPL), a modality in which flash lamps installed in an optical treatment device (head or tip) with mirrors to reflect light, has in recent times gained popularity in the management of this condition. Aim This systematic review aims to evaluate the efficacy, safety and adverse effects of IPL treatment for rosacea. Methods This systematic review was conducted in accordance with the Preferred Reporting Item for Systematic Reviews and Meta-Analysis. The electronic databases searched were Medline, PubMed and Scopus databases. The Risk of bias in non-randomised studies of interventions (ROBINS-I) and risk-of-bias tools for randomised trials (RoB-2) was employed to assess the risk of bias. Results Of a total of 233 articles retrieved from Medline, Scopus and PubMed databases, 14 studies qualified for final analysis. The studies included patients with Fitzpatrick skin types I to IV, with ages ranging from 15 to 78 years. Although the included studies showed heterogeneity between the parameters used, most studies demonstrated positive effects of IPL treatment on telangiectasia and erythema in rosacea and that the adverse effects presented were transitory. Limitation The methodological quality of the included studies was poor. Conclusion Although most studies showed the efficacy of IPL in the treatment of rosacea, the poor quality of the studies was of concern.
摘要：
背景酒渣鼻是一种以面部红斑为特征的皮肤慢性炎症性疾病,水肿,毛细血管扩张,丘疹,脓疱和结节。治疗酒渣鼻的有效治疗方法很少。强脉冲光(IPL),一种方式，其中闪光灯安装在光学治疗装置（头部或尖端）中，带有反射镜以反射光，最近在这种情况的管理中越来越受欢迎。目的本系统综述旨在评估疗效，IPL治疗酒渣鼻的安全性和不良反应。方法根据系统评价和Meta分析的首选报告项目进行系统评价。搜索的电子数据库是Medline,PubMed和Scopus数据库。非随机干预研究中的偏倚风险（ROBINS-I）和随机试验的偏倚风险工具（RoB-2）用于评估偏倚风险。结果在Medline检索到的233篇文章中，Scopus和PubMed数据库,14项研究符合最终分析条件。这些研究包括FitzpatrickI至IV型皮肤患者，年龄从15到78岁不等。尽管纳入的研究显示所使用的参数之间存在异质性，大多数研究表明,IPL治疗对酒渣鼻毛细血管扩张和红斑有积极作用,并且所呈现的不良反应是短暂的.限制纳入研究的方法学质量较差。结论虽然大部分研究显示IPL治疗酒渣鼻的疗效,研究质量差令人担忧.
