Abstract：
Central serous chorioretinopathy (CSC) is a common disorder characterized by serous retinal detachment. Several studies using indocyanine green angiography (ICGA) have revealed that choroidal filling delay, choroidal vascular dilation, and choroidal vascular hyperpermeability are the characteristic findings of CSC. These ICGA findings confirm that choroidal circulatory disturbances are the primary factors in the pathogenesis of CSC. With advancements in optical coherence tomography (OCT), choroidal thickness has been found to be significantly greater in eyes with CSC than in normal eyes. Dilated large choroidal vessels reportedly account for the thickened choroid in eyes with CSC. Although many possible mechanisms and risk factors have been suggested, the pathophysiologic features of choroidal circulatory disturbances and choroidal thickening in eyes with CSC have not yet been fully elucidated. Recently, using anterior segment OCT, we proposed that the sclera may induce choroidal circulatory disturbances since CSC eyes have significantly thicker sclera than do normal eyes. This review summarizes updated information on the close relationship between CSC pathogenesis and the sclera.
摘要：
中心性浆液性脉络膜视网膜病变(CSC)是以浆液性视网膜脱离为特征的常见疾病。使用吲哚菁绿血管造影术（ICGA）的几项研究表明，脉络膜充盈延迟，脉络膜血管扩张,脉络膜血管通透性过高是CSC的特征性表现。这些ICGA发现证实脉络膜循环障碍是CSC发病的主要因素。随着光学相干断层扫描（OCT）的进步，已发现CSC眼的脉络膜厚度明显大于正常眼。据报道，大脉络膜血管扩张是CSC眼中脉络膜增厚的原因。尽管已经提出了许多可能的机制和风险因素，CSC眼脉络膜循环障碍和脉络膜增厚的病理生理学特征尚未完全阐明。最近,使用眼前节OCT，我们提出巩膜可能会引起脉络膜循环障碍，因为CSC眼的巩膜比正常眼明显厚。这篇综述总结了关于CSC发病机制与巩膜之间密切关系的最新信息。
