Abstract：
In childhood drug-resistant focal epilepsy, the identification of a magnetic resonance imaging lesion significantly affects the management and prognosis, although it is often challenging. Herein we report the preliminary results of a modified MR sequence, in which both magnetization transfer and chemical shift selective preparation pulses are added to a 3D fast spin echo T1-weighted sequence to recognize focal cortical dysplasia. The scan time is short, and the images have expected uniform suppression of the background normal gray and white matter. We report four children with focal epilepsy, in whom the focal cortical and subcortical lesions are superiorly conspicuous on the aforementioned MR sequence compared to the high-resolution fluid-attenuated inversion recovery images obtained with typical epilepsy MR protocols.
摘要：
在儿童耐药局灶性癫痫中，磁共振成像病变的识别显着影响治疗和预后，虽然它经常具有挑战性。在这里，我们报告了改良的MR序列的初步结果，其中磁化转移和化学位移选择性准备脉冲都被添加到3D快速自旋回波T1加权序列中以识别局灶性皮质发育不良。扫描时间短,并且图像具有预期的背景正常灰质和白质的均匀抑制。我们报告了四名局灶性癫痫儿童，与使用典型的癫痫MR方案获得的高分辨率流体衰减反转恢复图像相比，在上述MR序列上，局灶性皮质和皮质下病变更为明显。
