关键词: MRONJ ONJ awareness bisphosphonate-associated osteonecrosis of the jaw knowledge medication-related osteonecrosis of the jaw osteonecrosis of the jaw patients

来  源:   DOI:10.3389/froh.2024.1441601   PDF(Pubmed)

Abstract:
UNASSIGNED: Medication-related osteonecrosis of the Jaw (MRONJ) is an adverse drug reaction that affects the mandible and maxilla of patients exposed to BMA and AA therapies, causing the progressive destruction and death of bone. To date, oral health preventive measures remain the most effective strategy to reduce MRONJ incidence, and, in this sense, the major goal is to diagnose, treat, and eradicate any oral diseases that could compromise oral health. The present systematic review aims to investigate the awareness of MRONJ among patients assuming BMAs.
UNASSIGNED: A systematic literature search was performed, selecting studies that concern the awareness of patients of the risk of MRONJ.
UNASSIGNED: Six studies were included in this review. In total, 483 patients were evaluated. Of the 483 included patients, 391 were not aware of the possibility of MRONJ onset (391/483, 81%) and 92 were aware of it (92/483, 19%).
UNASSIGNED: The problem of patient\'s lack of awareness with respect to MRONJ risk presents different layers of complexity (\"what?\", \"who?\", \"where?\", \"when?\" and \"why?\"). Among its causal factors, there are an inadequate level of communication with patients and the lack of collaboration between healthcare professionals, which is related to an individualistic view of liability and deontological duties. MRONJ is a drug adverse reaction that can greatly affect the quality of life of patients if not promptly diagnosed and treated. Therefore, patients must be fully aware of the risks of adverse and the importance of preventive measures, which imply effective and exhaustive communication by each member of the multidisciplinary team. Effective teamwork and collaborative care should be promoted to positively impact patients\' awareness.
摘要:
药物相关的颌骨坏死(MRONJ)是一种药物不良反应,会影响接受BMA和AA治疗的患者的下颌骨和上颌骨,导致骨骼的进行性破坏和死亡。迄今为止,口腔健康预防措施仍然是减少MRONJ发病率的最有效策略,and,在这个意义上,主要目标是诊断,请客,根除任何可能危害口腔健康的口腔疾病。本系统综述旨在调查假设BMA的患者对MRONJ的认识。
进行了系统的文献检索,选择关注患者对MRONJ风险认识的研究。
本综述包括6项研究。总的来说,对483例患者进行了评估。在483名患者中,391人不知道MRONJ发作的可能性(391/483,81%),92人知道(92/483,19%)。
患者对MRONJ风险缺乏认识的问题呈现出不同的复杂性(“什么?”,“谁?”“哪里?”,“什么时候?”和“为什么?”)。在其因果因素中,与患者的沟通水平不足,医疗保健专业人员之间缺乏合作,这与责任和义务义务的个人主义观点有关。MRONJ是一种药物不良反应,如果不及时诊断和治疗,会极大地影响患者的生活质量。因此,患者必须充分意识到不良风险和预防措施的重要性,这意味着多学科团队的每个成员进行有效和详尽的沟通。应促进有效的团队合作和协作护理,以积极影响患者的意识。
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