PDF(Pubmed)
Abstract：
Hypoglycemia is a rare complication of diffuse large B-cell lymphoma. We are presenting a case of 67-year-old woman presented to her primary care physician with fatigue and hyperhidrosis. Laboratory evaluation revealed a glucose level of 1.9 mmol/L. Computed tomographic scan of the abdomen and subsequent positron emission tomographic scan revealed extensive lymphadenopathy. The patient was then diagnosed with CD5-positive-diffuse large B-cell lymphoma and developed recurrent hypoglycemia despite continuous infusion of glucose. Following immunochemotherapy, hypoglycemia was resolved. Several explanations have been postulated but the exact pathophysiology is not well understood. Further investigation is warranted to more clearly define the pathophysiology of persistent hypoglycemia in patients with diffuse large B-cell lymphoma.
摘要：
低血糖是弥漫性大B细胞淋巴瘤的罕见并发症。我们正在向她的初级保健医生介绍一例67岁女性，患有疲劳和多汗症。实验室评估显示葡萄糖水平为1.9mmol/L。腹部计算机断层扫描和随后的正电子发射断层扫描显示广泛的淋巴结病。然后，患者被诊断为CD5阳性弥漫性大B细胞淋巴瘤，尽管持续输注葡萄糖，但仍出现复发性低血糖。免疫化疗后，低血糖得到解决。已经提出了几种解释，但确切的病理生理学尚不清楚。需要进一步研究以更清楚地定义弥漫性大B细胞淋巴瘤患者持续低血糖的病理生理学。
