p38 α 缺乏通过下调 STAT3 介导的角质形成细胞增殖和细胞因子产生来改善银屑病的发展。
Mesh : Psoriasis / metabolism genetics pathology STAT3 Transcription Factor / metabolism genetics Keratinocytes / metabolism Animals Cell Proliferation Mice Mitogen-Activated Protein Kinase 14 / metabolism genetics Cytokines / metabolism Down-Regulation Mice, Knockout Interleukin-17 / metabolism genetics Mice, Inbred C57BL Disease Models, Animal Signal Transduction Humans Imiquimod
来 源:
DOI:10.1038/s42003-024-06700-w
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