关键词: Diet therapy Eosinophilic esophagitis Food elimination diet Food hypersensitivity Formulated food

来  源:   DOI:10.1159/000540228   PDF(Pubmed)

Abstract:
UNASSIGNED: The effectiveness of dietary therapy to induce remission of eosinophilic esophagitis (EoE) has been evaluated over the last decades and summarized in meta-analyses. Choosing the dietary modality, identifying the most suitable patients, and implementing specific prerequisites are essential to ensure long-term success.
UNASSIGNED: Impractical exclusive elemental diets provided the highest remission rates in EoE; however, they are not recommended due to their numerous disadvantages and detrimental effects on patient quality of life. Allergy testing-guided diets for EoE are limited; their insufficient effectiveness and low reproducibility are due to poor accuracy of skin or serum test results in identifying EoE food triggers. Initial experiences with a six-food elimination diet have provided evidence of high and predictive effectiveness rates and paved the way for less restrictive and more efficient step-up approaches, including four-food, two-food, and most recently, milk elimination diets. Dietary treatment for EoE is challenging for patients and families and requires certain skills to ensure success in the short and long term.
UNASSIGNED: The selection of appropriate patients is essential to ensure the success of and long-term adherence to dietary treatment of EoE. As normal triggers for EoE are commonly found in the staple diet, it is important to ensure adequate nutritional substitutes to avoid nutrient deficiency risks when long-lasting feeding difficulties or extensive restrictions are present. Specialized facilities in dietary therapy should adopt patient-centered and personalized approaches in order to provide timely monitoring and support for complex cases.
摘要:
在过去的几十年中,已经评估了饮食疗法诱导嗜酸性粒细胞性食管炎(EoE)缓解的有效性,并在荟萃分析中进行了总结。选择饮食方式,找出最合适的病人,实施具体的先决条件对于确保长期成功至关重要。
不切实际的独家元素饮食在EoE中提供了最高的缓解率;然而,由于它们的许多缺点和对患者生活质量的不利影响,因此不推荐使用它们。EoE的过敏测试指导饮食是有限的;它们的有效性和可重复性不足是由于皮肤或血清测试结果在识别EoE食物触发因素方面的准确性差。六食消除饮食的初步经验提供了高有效性和预测有效性的证据,并为减少限制和更有效的逐步方法铺平了道路。包括四种食物,两种食物,最近,消除牛奶的饮食。EoE的饮食治疗对患者和家庭来说具有挑战性,需要一定的技能来确保短期和长期的成功。
选择合适的患者对于确保EoE饮食治疗的成功和长期坚持至关重要。由于EoE的正常触发因素通常存在于主食中,重要的是要确保足够的营养替代品,以避免营养缺乏风险时,长期的喂养困难或存在广泛的限制。饮食治疗的专业设施应采用以患者为中心和个性化的方法,以便为复杂病例提供及时的监测和支持。
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