PDF(Pubmed)
Abstract：
UNASSIGNED: People with schizophrenia and bipolar disorder are at increased risk of having comorbid somatic illness. This is partly due to lack of physical activity, which may originate from childhood. Sleep disturbances are associated with schizophrenia and bipolar disorder. We aimed to assess physical activity and sleep in children at familial high risk of schizophrenia or bipolar disorder and population-based controls.
UNASSIGNED: This study is part of The Danish High Risk and Resilience Study-VIA 11. Children aged 11 born to parents with schizophrenia (FHR-SZ) (N = 133), bipolar disorder (FHR-BP) (N = 84), or controls (C) (N = 150) were assessed by accelerometry for an average of 6.9 days.
UNASSIGNED: High-intensity physical activity was significantly lower in children at FHR-SZ and FHR-BP compared to controls, (mean hours per day for FHR-SZ: 0.29, SD 0.19, for FHR-BP: 0.27, SD 0.24, and for controls 0.38, SD 0.22, P = <.001). Sleep did not differ between the groups.
UNASSIGNED: Children at FHR-SZ or FHR-BP had less physical activity compared to controls. Our study highlights a research area that reveals a hitherto unexplored disadvantage of being born to parents with schizophrenia or bipolar disorder. Further research is needed to enhance better understanding of causal pathways and consequences of reduced physical activity in children with FHR-SZ and FHR-BP.
UNASSIGNED: This study is part of The Danish High Risk and Resilience Study-VIA 11. Children aged 11 born to parents with schizophrenia (FHR-SZ) (N = 133), bipolar disorder (FHR-BP) (N = 84), or controls (C) (N = 150) were assessed by accelerometry for an average of 6.9 days.
UNASSIGNED: High-intensity physical activity was significantly lower in children at FHR-SZ and FHR-BP compared to controls, (mean hours per day for FHR-SZ: 0.29, SD 0.19, for FHR-BP: 0.27, SD 0.24, and for controls 0.38, SD 0.22, P = <.001). Sleep did not differ between the groups.
UNASSIGNED: Children at FHR-SZ or FHR-BP had less physical activity compared to controls. Our study highlights a research area that reveals a hitherto unexplored disadvantage of being born to parents with schizophrenia or bipolar disorder. Further research is needed to enhance better understanding of causal pathways and consequences of reduced physical activity in children with FHR-SZ and FHR-BP.
摘要：
患有精神分裂症和双相情感障碍的人患躯体疾病的风险增加。这部分是由于缺乏体力活动，这可能源于童年。睡眠障碍与精神分裂症和双相情感障碍有关。我们旨在评估精神分裂症或双相情感障碍家族高风险儿童的身体活动和睡眠以及基于人群的控制。
■本研究是丹麦高风险和弹性研究的一部分-VIA11。父母所生的11岁儿童患有精神分裂症（FHR-SZ）（N=133），双相情感障碍（FHR-BP）（N=84），或对照(C)(N=150)通过加速度测定法平均6.9天进行评估。
■与对照组相比，FHR-SZ和FHR-BP的儿童高强度体力活动明显较低，(FHR-SZ每天平均小时数:0.29,SD0.19,FHR-BP每天平均小时数:0.27,SD0.24,对照0.38,SD0.22,P=<.001)。两组之间的睡眠没有差异。
■与对照组相比，FHR-SZ或FHR-BP的儿童体力活动较少。我们的研究强调了一个研究领域，该领域揭示了精神分裂症或躁郁症父母所生的迄今为止尚未探索的缺点。需要进一步的研究，以更好地理解FHR-SZ和FHR-BP儿童体力活动减少的因果途径和后果。
■本研究是丹麦高风险和弹性研究的一部分-VIA11。父母所生的11岁儿童患有精神分裂症（FHR-SZ）（N=133），双相情感障碍（FHR-BP）（N=84），或对照(C)(N=150)通过加速度测定法平均6.9天进行评估。
■与对照组相比，FHR-SZ和FHR-BP的儿童高强度体力活动明显较低，(FHR-SZ每天平均小时数:0.29,SD0.19,FHR-BP每天平均小时数:0.27,SD0.24,对照0.38,SD0.22,P=<.001)。两组之间的睡眠没有差异。
■与对照组相比，FHR-SZ或FHR-BP的儿童体力活动较少。我们的研究强调了一个研究领域，该领域揭示了精神分裂症或躁郁症父母所生的迄今为止尚未探索的缺点。需要进一步的研究，以更好地理解FHR-SZ和FHR-BP儿童体力活动减少的因果途径和后果。
