PDF(Pubmed)
Abstract：
UNASSIGNED: To compare the ocular blood flow in glaucomatous eyes and normal healthy eyes. This study compares open-angle glaucoma patients to healthy adults by measuring various parameters in the ophthalmic artery (OA), central retinal artery (CRA), and short posterior ciliary artery (SPCA).
UNASSIGNED: A total of 50 glaucomatous eyes and 50 normal eyes were included in a prospective case-control study over 1 year. The color Doppler imaging (CDI) was conducted using a noninvasive linear multifrequency probe with a frequency range of 5-9 MHz. OA, CRA, and SPCA were measured for peak systolic velocity (PSV), end-diastolic volume (EDV), pulsatility index (PI), and resistivity index (RI).
UNASSIGNED: When compared with controls, PSV was decreased in all three vessels, with the results being remarkable only in CRA. The EDV also showed a remarkable decrease in all three vessels. Additionally, all three vessels showed significant increases in PI and RI except OA, p-value < 0.05.
UNASSIGNED: Blood velocity is decreased, and resistive indices are increased in glaucomatous eyes compared with normal eyes. Variations in ocular blood flow could be a cause or consequence of glaucomatous optic neuropathy and are an important predictor of disease progression.
UNASSIGNED: Murugesan MAD, Venkat P, Basetti B. Comparison of Ocular Blood Flow in Glaucomatous Eyes and Nonglaucomatous Eyes at a Tertiary Hospital in South India: A Prospective Case-control Study. J Curr Glaucoma Pract 2024;18(2):45-50.
UNASSIGNED: A total of 50 glaucomatous eyes and 50 normal eyes were included in a prospective case-control study over 1 year. The color Doppler imaging (CDI) was conducted using a noninvasive linear multifrequency probe with a frequency range of 5-9 MHz. OA, CRA, and SPCA were measured for peak systolic velocity (PSV), end-diastolic volume (EDV), pulsatility index (PI), and resistivity index (RI).
UNASSIGNED: When compared with controls, PSV was decreased in all three vessels, with the results being remarkable only in CRA. The EDV also showed a remarkable decrease in all three vessels. Additionally, all three vessels showed significant increases in PI and RI except OA, p-value < 0.05.
UNASSIGNED: Blood velocity is decreased, and resistive indices are increased in glaucomatous eyes compared with normal eyes. Variations in ocular blood flow could be a cause or consequence of glaucomatous optic neuropathy and are an important predictor of disease progression.
UNASSIGNED: Murugesan MAD, Venkat P, Basetti B. Comparison of Ocular Blood Flow in Glaucomatous Eyes and Nonglaucomatous Eyes at a Tertiary Hospital in South India: A Prospective Case-control Study. J Curr Glaucoma Pract 2024;18(2):45-50.
摘要：
■比较青光眼和正常健康眼睛的眼部血流量。这项研究通过测量眼动脉（OA）的各种参数，将开角型青光眼患者与健康成年人进行比较。视网膜中央动脉(CRA),睫状后动脉短（SPCA）。
■一项为期1年的前瞻性病例对照研究共纳入50只青光眼和50只正常眼。彩色多普勒成像（CDI）是使用频率范围为5-9MHz的非侵入性线性多频探头进行的。OA,CRA,和SPCA测量收缩期峰值速度（PSV），舒张末期容积(EDV),搏动指数(PI),和电阻率指数(RI)。
■与对照组相比，三支血管的PSV都下降了，结果仅在CRA中显著。EDV在所有三个血管中也显示出显着的下降。此外,除OA外，所有三个血管的PI和RI均显着增加，p值<0.05。
■血流速度降低，与正常眼相比，青光眼的电阻指数增加。眼血流的变化可能是青光眼性视神经病变的原因或结果，并且是疾病进展的重要预测指标。
■MurugesanMAD,VenkatP,BasettiB.印度南部三级医院青光眼和非青光眼眼部血流的比较：一项前瞻性病例对照研究。JCurr青光眼Pract2024；18（2）：45-50。
■一项为期1年的前瞻性病例对照研究共纳入50只青光眼和50只正常眼。彩色多普勒成像（CDI）是使用频率范围为5-9MHz的非侵入性线性多频探头进行的。OA,CRA,和SPCA测量收缩期峰值速度（PSV），舒张末期容积(EDV),搏动指数(PI),和电阻率指数(RI)。
■与对照组相比，三支血管的PSV都下降了，结果仅在CRA中显著。EDV在所有三个血管中也显示出显着的下降。此外,除OA外，所有三个血管的PI和RI均显着增加，p值<0.05。
■血流速度降低，与正常眼相比，青光眼的电阻指数增加。眼血流的变化可能是青光眼性视神经病变的原因或结果，并且是疾病进展的重要预测指标。
■MurugesanMAD,VenkatP,BasettiB.印度南部三级医院青光眼和非青光眼眼部血流的比较：一项前瞻性病例对照研究。JCurr青光眼Pract2024；18（2）：45-50。
