关键词: EN-DCR anesthesia effect articaine endoscopic endonasal dacryocystorhinostomy lidocaine

来  源:   DOI:10.3389/fmed.2024.1332793   PDF(Pubmed)

Abstract:
UNASSIGNED: To investigate the comparative effects of local anesthesia using lidocaine with adrenaline vs. articaine with adrenaline in endoscopic endonasal dacryocystorhinostomy (EN-DCR).
UNASSIGNED: This retrospective study included a total of 180 patients. These patients were categorized into two groups: the lidocaine group, which received 2% lidocaine (1:100,000 adrenaline), and the articaine group, which received 4% articaine (1:100,000 adrenaline) for local anesthesia. The study compared anesthesia efficacy, intraoperative pain levels, intraoperative bleeding, as well as differences in heart rate and blood pressure between the two groups.
UNASSIGNED: The articaine group demonstrated a significantly lower visual analog scale (VAS) pain score when compared to the lidocaine group, measuring at 4.4 ± 0.6 cm vs. 5.0 ± 1.0 cm, respectively (P < 0.0001). Additionally, the articaine group exhibited a higher anesthesia efficacy compared to the lidocaine group (89.0% vs. 76.6%, p = 0.0487). Notably, the articaine group experienced less nasal mucosal bleeding during the surgery in contrast to the lidocaine group (p = 0.004). However, there were no statistically significant differences in changes in blood pressure and heart rate between the two groups (p > 0.05).
UNASSIGNED: This study demonstrated that 4% articaine (1:100,000 adrenaline) has superior clinical effectiveness in comparison to 2% lidocaine (1:100,000 adrenaline) in EN-DCR.
摘要:
研究利多卡因与肾上腺素局部麻醉的比较效果阿替卡因与肾上腺素在鼻内镜泪囊鼻腔吻合术(EN-DCR)中的应用。
这项回顾性研究共包括180名患者。这些患者分为两组:利多卡因组,接受2%利多卡因(1:100,000肾上腺素),阿替卡因组,接受4%阿替卡因(1:100,000肾上腺素)局部麻醉。该研究比较了麻醉效果,术中疼痛水平,术中出血,以及两组之间心率和血压的差异。
阿替卡因组与利多卡因组相比,显示出明显较低的视觉模拟评分(VAS)疼痛评分,测量在4.4±0.6厘米与5.0±1.0cm,分别为(P<0.0001)。此外,与利多卡因组相比,阿替卡因组表现出更高的麻醉效果(89.0%vs.76.6%,p=0.0487)。值得注意的是,与利多卡因组相比,阿替卡因组手术期间鼻粘膜出血较少(p=0.004).然而,两组患者血压、心率变化差异无统计学意义(p>0.05)。
这项研究表明,与EN-DCR中的2%利多卡因(1:100,000肾上腺素)相比,4%阿替卡因(1:100,000肾上腺素)具有更好的临床疗效。
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