PDF(Pubmed)
Abstract：
Heart failure (HF) remains a progressive syndrome with high morbidity and mortality, and accounts for many hospitalisations globally with a downstream impact of increasing healthcare costs. South Asian individuals account for most of the global burden of non-communicable diseases. In this systematic review, a literature search was performed for all studies focusing on South Asians and HF using PubMed as the primary research tool and citations were included from relevant MEDLINE-indexed journals. Upon identification of relevant studies, pertinent data points were extracted systematically from each eligible study. South Asians have an earlier age of onset of many non-communicable diseases compared to other ethnic groups worldwide, including cardiovascular disease (CVD). Given the large number of South Asians impacted by CVD and both traditional and non-traditional risk factors for CVD, HF has the potential to become an epidemic among South Asians across the world. Individuals of South Asian origin are at elevated risk for CVD compared to many other populations and should be followed closely for the potential development of HF. This review describes what is unique to South Asian individuals at risk for and with established HF, as well as management and prognostic considerations. Future directions and potential policy changes are highlighted that can reduce the HF burden among South Asians globally.
摘要：
心力衰竭（HF）仍然是一种具有高发病率和死亡率的进行性综合征，并占全球许多住院治疗的原因，其下游影响是医疗费用的增加。南亚个人占全球非传染性疾病负担的大部分。在这次系统审查中，使用PubMed作为主要研究工具,对所有针对南亚人和HF的研究进行了文献检索,并纳入了相关MEDLINE索引期刊的引文.在确定相关研究后，从每项符合条件的研究中系统提取相关数据点.与全世界其他种族相比，南亚人许多非传染性疾病的发病年龄较早，包括心血管疾病（CVD）。鉴于大量南亚人受到CVD的影响，以及CVD的传统和非传统风险因素，HF有可能成为世界各地南亚人的流行病。与许多其他人群相比，南亚血统的个体患CVD的风险较高，应密切关注HF的潜在发展。这篇综述描述了什么是独特的南亚个人在风险和建立HF，以及管理和预后考虑。强调了未来的方向和潜在的政策变化，可以减轻全球南亚人的HF负担。
