UNASSIGNED: This retrospective, single-center cohort study included 346 participants aged 65 and above who underwent surgical treatment for hip fractures. We compared mortality rates between the pre-COVID and COVID eras. Data included demographics, treatment, complications, and COVID-19 status. The independent samples t test and Chi-square tests (or Fisher\'s exact test) were used for comparisons for era cohorts. Survival probabilities were assessed using Kaplan-Meier, while multivariate analysis identified mortality predictors.
UNASSIGNED: 175 patients were included in the pre-COVID era, and 171 patients were included in the COVID era. During the COVID era, the 30-day mortality rate was 11.7% (compared to 13.7% in the pre-COVID era, p = 0.573), and the 1-year mortality rate was 43.9% (compared to 49.1% in the pre-COVID era, p = 0.325). The overall 1-year mortality rate was 46.5%. Patients who underwent surgery within 48 hours had a higher 1-year survival rate (60.5%) compared to those with delayed surgery (51.2%), p = 0.031. Additionally, patients not admitted to the ICU had a higher 1-year survival rate (74.7%) than those who were admitted (44.9%), p < 0.001. 70.1% of the total deaths occurred within the first 90 days.
UNASSIGNED: Elderly patients with hip fractures experienced high mortality rates before and during the pandemic. This study demonstrates that the 1-year mortality rates of geriatric hip fractures were not significantly affected by the pandemic. The findings emphasize the importance of pandemic preparedness and prompt surgeries and attentive ICU care in reducing mortality rates.
■这次回顾展,单中心队列研究纳入了346名年龄在65岁及以上且因髋部骨折接受手术治疗的参与者.我们比较了COVID前期和COVID时代的死亡率。数据包括人口统计,治疗,并发症,和COVID-19状态。使用独立样本t检验和卡方检验(或Fisher精确检验)进行年龄队列的比较。使用Kaplan-Meier评估生存概率,而多变量分析确定了死亡率预测因素。
■175名患者被纳入前COVID时代,171例患者被纳入COVID时代。在COVID时代,30天死亡率为11.7%(相比之下,新冠肺炎前期为13.7%,p=0.573),1年死亡率为43.9%(相比之下,前COVID时代为49.1%,p=0.325)。1年总死亡率为46.5%。在48小时内接受手术的患者的1年生存率(60.5%)高于延迟手术的患者(51.2%),p=0.031。此外,未进入ICU的患者的1年生存率(74.7%)高于入院的患者(44.9%),p<0.001。总死亡人数的70.1%发生在前90天内。
■老年髋部骨折患者在大流行之前和期间经历了高死亡率。这项研究表明,老年髋部骨折的1年死亡率并未受到大流行的影响。研究结果强调了大流行防备,及时手术和关注ICU护理在降低死亡率方面的重要性。