PDF(Pubmed)
Abstract：
UNASSIGNED: Inflammatory myofibroblastic tumor (IMT) is a rare entity, classified within soft tissue sarcomas. It is an intermediate malignancy tumor, which seldom presents as metastatic disease. The treatment of choice is surgery, except in cases where surgery is not possible due to localization or if it presents with metastatic disease. Approximately 50% of IMTs will exhibit ALK translocation, providing a therapeutic target for these patients.
UNASSIGNED: A case is presented of a patient with metastatic IMT in complete response to treatment with alectinib, maintained for over 4 years.
UNASSIGNED: This case showed a long time complete response in patient with IMT treated with alectinib.
UNASSIGNED: A case is presented of a patient with metastatic IMT in complete response to treatment with alectinib, maintained for over 4 years.
UNASSIGNED: This case showed a long time complete response in patient with IMT treated with alectinib.
摘要：
■炎性肌纤维母细胞瘤（IMT）是一种罕见的实体，分类在软组织肉瘤。这是一种中间恶性肿瘤，很少表现为转移性疾病。选择的治疗方法是手术，除非由于定位或存在转移性疾病而无法进行手术。大约50%的IMT会表现出ALK易位，为这些患者提供治疗靶点。
■一例患者患有转移性IMT，对阿来替尼治疗完全缓解，维持4年以上。
■该病例在接受阿来替尼治疗的IMT患者中显示出长时间的完全反应。
■一例患者患有转移性IMT，对阿来替尼治疗完全缓解，维持4年以上。
■该病例在接受阿来替尼治疗的IMT患者中显示出长时间的完全反应。
