PDF(Pubmed)
Abstract：
UNASSIGNED: Disturbance of circadian rhythms caused by shift work has adverse effects on insulin resistance. Many previous studies have confirmed that shift work and insulin resistance are related using homeostasis model assessment-insulin resistance, one of the insulin resistance indicators. However, the triglycerides and glucose index (TyG index) has recently been studied as an insulin resistance indicator. The aim of this study is to investigate the association of shift work and TyG index, one of the indirect indicators of insulin resistance, using results of health checkups in one workplace.
UNASSIGNED: Based on medical examination data collected in February 2019, a total of 3,794 subjects from one chemical plant in Korea were selected for this study. Cut-off value of TyG index for predicting development of diabetes mellitus (DM) was 4.69. A multiple logistic regression analysis was performed after adjusting for age, employment period, obesity, abdominal obesity, smoking, drinking, physical activity, hypertension, stroke, heart disease.
UNASSIGNED: As a result of logistic regression analysis, compared to day workers, odds ratio (OR) with a TyG index above cut-off value for predicting development of DM in shift workers was 1.220 after adjusting for age, employment period, obesity, abdominal obesity, smoking, drinking, physical activity, hypertension, stroke, heart disease (Model 1, OR: 1.276; 95% confidence interval [CI]: 1.099-1.482; Model 2, OR: 1.232; 95% CI: 1.055-1.438; Model 3, OR: 1.220, 95% CI: 1.030-1.444).
UNASSIGNED: There was a significant association between shift work and TyG index among male workers in a chemical plant. More research studies on the association between shift work and TyG index are needed in the future.
UNASSIGNED: Based on medical examination data collected in February 2019, a total of 3,794 subjects from one chemical plant in Korea were selected for this study. Cut-off value of TyG index for predicting development of diabetes mellitus (DM) was 4.69. A multiple logistic regression analysis was performed after adjusting for age, employment period, obesity, abdominal obesity, smoking, drinking, physical activity, hypertension, stroke, heart disease.
UNASSIGNED: As a result of logistic regression analysis, compared to day workers, odds ratio (OR) with a TyG index above cut-off value for predicting development of DM in shift workers was 1.220 after adjusting for age, employment period, obesity, abdominal obesity, smoking, drinking, physical activity, hypertension, stroke, heart disease (Model 1, OR: 1.276; 95% confidence interval [CI]: 1.099-1.482; Model 2, OR: 1.232; 95% CI: 1.055-1.438; Model 3, OR: 1.220, 95% CI: 1.030-1.444).
UNASSIGNED: There was a significant association between shift work and TyG index among male workers in a chemical plant. More research studies on the association between shift work and TyG index are needed in the future.
摘要：
■轮班工作引起的昼夜节律紊乱对胰岛素抵抗有不利影响。以前的许多研究已经证实，轮班工作与胰岛素抵抗有关，使用稳态模型评估-胰岛素抵抗，胰岛素抵抗指标之一。然而,最近研究了甘油三酯和葡萄糖指数(TyG指数)作为胰岛素抵抗指标。这项研究的目的是调查轮班工作与TyG指数的关系，胰岛素抵抗的间接指标之一，在一个工作场所使用健康检查的结果。
■根据2019年2月收集的医学检查数据，本研究共选择了来自韩国一家化工厂的3,794名受试者。预测糖尿病（DM）发展的TyG指数的临界值为4.69。校正年龄后进行多元logistic回归分析，就业期,肥胖，腹部肥胖，吸烟,饮酒,身体活动,高血压,中风,心脏病。
■作为逻辑回归分析的结果，与日工相比，预测轮班工人DM发展的TyG指数高于临界值的比值比（OR）在调整年龄后为1.220，就业期,肥胖，腹部肥胖，吸烟,饮酒,身体活动,高血压,中风,心脏病（模型1，OR：1.276；95%置信区间[CI]：1.099-1.482；模型2，OR：1.232；95%CI：1.055-1.438；模型3，OR：1.220，95%CI：1.030-1.444）。
■在化工厂的男性工人中，轮班工作与TyG指数之间存在显着关联。未来需要更多关于轮班工作与TyG指数之间关联的研究。
■根据2019年2月收集的医学检查数据，本研究共选择了来自韩国一家化工厂的3,794名受试者。预测糖尿病（DM）发展的TyG指数的临界值为4.69。校正年龄后进行多元logistic回归分析，就业期,肥胖，腹部肥胖，吸烟,饮酒,身体活动,高血压,中风,心脏病。
■作为逻辑回归分析的结果，与日工相比，预测轮班工人DM发展的TyG指数高于临界值的比值比（OR）在调整年龄后为1.220，就业期,肥胖，腹部肥胖，吸烟,饮酒,身体活动,高血压,中风,心脏病（模型1，OR：1.276；95%置信区间[CI]：1.099-1.482；模型2，OR：1.232；95%CI：1.055-1.438；模型3，OR：1.220，95%CI：1.030-1.444）。
■在化工厂的男性工人中，轮班工作与TyG指数之间存在显着关联。未来需要更多关于轮班工作与TyG指数之间关联的研究。
