PDF(Pubmed)
Abstract：
UNASSIGNED: Sleeping disorders were reported in many patients who took vaccines during previous pandemics. We aim to investigate the relationship between coronavirus disease 2019 (COVID-19) vaccines and the incidence of narcolepsy symptoms in the Jordanian population.
UNASSIGNED: We used a descriptive, cross-sectional, online self-administered survey conducted between December 2022 and May 2023. The survey targeted males and females above the age of 18 years who took any type of COVID-19 vaccine, had no chronic diseases, and had no sleep disorders prior to taking the vaccine. The survey was distributed via social media platforms.
UNASSIGNED: A total of 873 participants were included in this study, consisting of 44.4% males and 55.6% females, with the majority being in the 18-29 age group. Most participants (79.8%) received two vaccine doses, with the Pfizer vaccine being the most common. Nearly half of the participants reported excessive daytime sleepiness. Sleep paralysis and hypnagogic hallucinations were reported by a notable proportion of participants, but no significant differences were found among the vaccine types. Sleep attacks and fragmented nighttime sleep were associated with the number of vaccine doses received, suggesting a possible influence of the dose count on these symptoms. The presence of excessive daytime sleepiness, sudden loss of muscle tone, sleep paralysis, and hypnagogic hallucinations showed no significant association with the number of doses taken.
UNASSIGNED: We hypothesize a possible link between COVID-19 vaccination and the emergence of narcolepsy symptoms in Jordanian individuals. Additional investigations and continuous monitoring to determine the extent of the risk and uncover potential mechanisms behind this connection should be performed.
UNASSIGNED: We used a descriptive, cross-sectional, online self-administered survey conducted between December 2022 and May 2023. The survey targeted males and females above the age of 18 years who took any type of COVID-19 vaccine, had no chronic diseases, and had no sleep disorders prior to taking the vaccine. The survey was distributed via social media platforms.
UNASSIGNED: A total of 873 participants were included in this study, consisting of 44.4% males and 55.6% females, with the majority being in the 18-29 age group. Most participants (79.8%) received two vaccine doses, with the Pfizer vaccine being the most common. Nearly half of the participants reported excessive daytime sleepiness. Sleep paralysis and hypnagogic hallucinations were reported by a notable proportion of participants, but no significant differences were found among the vaccine types. Sleep attacks and fragmented nighttime sleep were associated with the number of vaccine doses received, suggesting a possible influence of the dose count on these symptoms. The presence of excessive daytime sleepiness, sudden loss of muscle tone, sleep paralysis, and hypnagogic hallucinations showed no significant association with the number of doses taken.
UNASSIGNED: We hypothesize a possible link between COVID-19 vaccination and the emergence of narcolepsy symptoms in Jordanian individuals. Additional investigations and continuous monitoring to determine the extent of the risk and uncover potential mechanisms behind this connection should be performed.
摘要：
■许多在以前的大流行期间接种疫苗的患者报告了睡眠障碍。我们的目的是调查2019年冠状病毒病（COVID-19）疫苗与约旦人群发作性睡病症状发生率之间的关系。
■我们使用了一个描述性的，横截面,2022年12月至2023年5月之间进行的在线自我管理调查。这项调查针对18岁以上的男性和女性，他们服用了任何类型的COVID-19疫苗，没有慢性疾病，在接种疫苗之前没有睡眠障碍。该调查是通过社交媒体平台发布的。
■本研究共纳入873名参与者，由44.4%的男性和55.6%的女性组成，大多数在18-29岁年龄段。大多数参与者（79.8%）接受了两剂疫苗，辉瑞疫苗是最常见的。近一半的参与者报告白天过度嗜睡。相当比例的参与者报告了睡眠麻痹和催眠幻觉，但是在疫苗类型之间没有发现显着差异。睡眠发作和零散的夜间睡眠与接受的疫苗剂量有关，提示剂量计数对这些症状的可能影响。白天过度嗜睡的存在，突然失去肌肉张力，睡眠麻痹,和催眠幻觉显示与服用剂量没有显著关联。
■我们假设COVID-19疫苗接种与约旦个体发作性睡病症状的出现之间可能存在联系。应进行额外的调查和持续监测，以确定风险的程度，并发现这种联系背后的潜在机制。
■我们使用了一个描述性的，横截面,2022年12月至2023年5月之间进行的在线自我管理调查。这项调查针对18岁以上的男性和女性，他们服用了任何类型的COVID-19疫苗，没有慢性疾病，在接种疫苗之前没有睡眠障碍。该调查是通过社交媒体平台发布的。
■本研究共纳入873名参与者，由44.4%的男性和55.6%的女性组成，大多数在18-29岁年龄段。大多数参与者（79.8%）接受了两剂疫苗，辉瑞疫苗是最常见的。近一半的参与者报告白天过度嗜睡。相当比例的参与者报告了睡眠麻痹和催眠幻觉，但是在疫苗类型之间没有发现显着差异。睡眠发作和零散的夜间睡眠与接受的疫苗剂量有关，提示剂量计数对这些症状的可能影响。白天过度嗜睡的存在，突然失去肌肉张力，睡眠麻痹,和催眠幻觉显示与服用剂量没有显著关联。
■我们假设COVID-19疫苗接种与约旦个体发作性睡病症状的出现之间可能存在联系。应进行额外的调查和持续监测，以确定风险的程度，并发现这种联系背后的潜在机制。
