Mesh : Animals Humans Helminths / immunology CD4-Positive T-Lymphocytes / immunology Helminthiasis / immunology parasitology Host-Parasite Interactions / immunology Mice

来  源:   DOI:10.1016/j.immuni.2024.07.014

Abstract:
Understanding determinants of immune response variation is central to developing treatment options. Even et al. show that naive CD4+ T cell transcriptional heterogeneity is altered by helminth infection leading to impaired immune responses independent of commensals.
摘要:
了解免疫反应变化的决定因素对于开发治疗方案至关重要。甚至等人。显示蠕虫感染改变了幼稚的CD4T细胞转录异质性,导致独立于共生体的免疫应答受损。
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