微孢子虫 EnP1 改变宿主细胞 H2B 单倍比素化并防止铁凋亡促进微孢子虫存活。
关键词: EnP1 ferroptosis histone H2B microsporidia nucleus-targeted effector
Mesh : Ubiquitination Ferroptosis Microsporidia / metabolism genetics Histones / metabolism Humans Fungal Proteins / metabolism genetics Tumor Suppressor Protein p53 / metabolism genetics Host-Pathogen Interactions Animals Cell Nucleus / metabolism Amino Acid Transport System y+ / metabolism genetics Microsporidiosis / metabolism
来 源:
DOI:10.1073/pnas.2400657121
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