关键词: Cardiovascular disease Cardiovascular disease prevention Cardiovascular outcomes Hypertension Time in target range Time in therapeutic range

来  源:   DOI:10.1007/s11886-024-02111-9

Abstract:
OBJECTIVE: To examine the concept of time in target range for blood pressure (BP) management, exploring its calculation methods, implications for patient outcomes, and potential use in patient care.
RESULTS: Recent post-hoc analyses of clinical trials and observational studies highlight the importance of BP time in target range in predicting cardiovascular outcomes. Higher time in target range correlates with reduced risks of major adverse cardiovascular events including heart failure, stroke, myocardial infarction and all-cause mortality. Additionally, longer time in target range decreases the risk of incident atrial fibrillation and risk of developing dementia. BP time in target range is a novel metric offering valuable insights into BP control and its impact on clinical outcomes. Higher time in target range is consistently associated with better cardiovascular outcomes across various patient populations. However, the clinical application of BP time in target range requires further investigation through prospective clinical trials and real-world studies. Integrating wearable devices for continuous BP monitoring could enhance the practical utility of BP time in target range in hypertension management.
摘要:
目的:研究血压(BP)管理的目标范围内的时间概念,探索其计算方法,对患者预后的影响,以及在病人护理中的潜在用途。
结果:最近对临床试验和观察性研究的事后分析强调了BP时间在目标范围内预测心血管结局的重要性。在目标范围内的时间延长与包括心力衰竭在内的主要不良心血管事件的风险降低相关。中风,心肌梗死和全因死亡率。此外,在目标范围内的时间越长,发生房颤的风险和发生痴呆的风险就会降低.目标范围内的BP时间是一种新颖的指标,可提供有关BP控制及其对临床结果的影响的有价值的见解。在不同的患者群体中,目标范围内的较高时间始终与更好的心血管结局相关。然而,BP时间在目标范围内的临床应用需要通过前瞻性临床试验和真实世界研究进行进一步研究.集成可穿戴设备进行连续BP监测可以提高BP时间在高血压管理目标范围内的实用性。
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