Abstract：
ChIP-Seq has been used extensively to profile genome-wide transcription factor binding and post-translational histone modifications. A sequential ChIP assay determines the in vivo co-localization of two proteins to the same genomic locus. In this chapter, we combine the two protocols in Sequential ChIP-Seq, a method for identifying genome-wide sites of in vivo protein co-occupancy.
摘要：
ChIP-Seq已被广泛用于描述全基因组转录因子结合和翻译后组蛋白修饰。顺序ChIP测定确定两种蛋白质在相同基因组基因座的体内共定位。在这一章中,我们将这两个协议组合在顺序ChIP-Seq中，用于鉴定体内蛋白质共占据的全基因组位点的方法。
