细胞外乙酰肝素硫酸酶 SULF2 限制炎性关节炎中髓样 IFN β 信号传导和 Th17 应答。
关键词: Heparan sulfate Inflammation Interferon Macrophage
Mesh : Animals Th17 Cells / immunology metabolism Signal Transduction Mice Macrophages / metabolism immunology Mice, Inbred C57BL Sulfatases / metabolism genetics Sulfotransferases / metabolism genetics Myeloid Cells / metabolism immunology Arthritis, Experimental / immunology pathology metabolism Arthritis, Rheumatoid / immunology metabolism pathology Inflammation / metabolism pathology Mice, Knockout Interleukin-6 / metabolism genetics Heparitin Sulfate / metabolism
来 源:
DOI:10.1007/s00018-024-05333-w
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