Abstract：
Rosettes and pseudorosettes are morphologic cell arrangements found in many neuroepithelial neoplasms in human medicine, including embryonal nervous system tumors (neuroblastoma, medulloblastoma, pineoblastoma, and retinoblastoma), non-embryonal nervous system tumors (ependymoma, astrocytoma, oligodendroglioma, and choroid plexus tumors), and other extraneural neuroepithelial neoplasms. Although these structures are also described in neuroepithelial neoplasms of domestic animals, their frequency is still poorly characterized or inconsistently documented in veterinary medicine. Furthermore, rosettes and pseudorosettes need to be interpreted with caution and within a clinical and pathologic context and should not be solely relied upon for diagnostic confirmation of a particular neoplasm. Here, we review the morphologic features and frequency of the most common types of rosettes and pseudorosettes described in neuroepithelial neoplasms of domestic animals, focusing primarily on those occurring in the nervous system and closely associated tissues.
摘要：
玫瑰花结和假玫瑰花结是人类医学中许多神经上皮肿瘤中发现的形态学细胞排列。包括胚胎神经系统肿瘤（神经母细胞瘤，髓母细胞瘤,松果体母细胞瘤,和视网膜母细胞瘤)，非胚胎神经系统肿瘤（室管膜瘤，星形细胞瘤,少突胶质细胞瘤,和脉络丛肿瘤)，和其他神经外神经上皮肿瘤。尽管这些结构在家畜的神经上皮肿瘤中也有描述，它们的频率在兽医学中仍然缺乏表征或记录不一致。此外，玫瑰花结和假玫瑰花结需要谨慎地在临床和病理背景下进行解释,不应仅仅依赖于特定肿瘤的诊断确认.这里,我们回顾了在家畜神经上皮肿瘤中描述的最常见类型的玫瑰花结和假玫瑰花结的形态学特征和频率。主要集中在那些发生在神经系统和密切相关的组织。
