UNASSIGNED: A systematic review and meta-analysis were performed. The primary outcome for the meta-analysis was long-term AF recurrence. Following the results of the meta-analysis, the cost-effectiveness of CBA versus RFA in Japan was assessed.
UNASSIGNED: The meta-analysis included 12 randomized controlled trials and six propensity-score matching cohort studies. AF recurrence was slightly lower in patients referred for CBA than for RFA, with an integrated risk ratio of 0.93 (95% confidence interval: 0.81-1.07) and an integrated hazard ratio of 0.96 (95% confidence interval: 0.77-1.19), but no significant difference was found. A cost-minimization analysis was conducted to compare the medical costs of CBA versus RFA because there was no significant difference in the risk of AF recurrence between the procedures. The estimated costs for CBA and RFA were JPY 4 858 544 (USD 32 390) and JPY 4 505 255 (USD 30 035), respectively, with cost savings for RFA of JPY 353 289 (USD 2355).
UNASSIGNED: Our meta-analysis suggests that CBA provides comparable benefits with regard to AF recurrence compared with RFA, as shown in previous studies. Although the choice of treatment should be based on patient and treatment characteristics, RFA was shown that it might be cost saving as compared to CBA.
■进行了系统评价和荟萃分析。荟萃分析的主要结果是长期房颤复发。根据荟萃分析的结果,评估了日本CBA与RFA的成本效益.
■荟萃分析包括12项随机对照试验和6项倾向评分匹配队列研究。接受CBA治疗的患者房颤复发率略低于接受RFA治疗的患者。综合风险比为0.93(95%置信区间:0.81-1.07),综合风险比为0.96(95%置信区间:0.77-1.19),但没有发现显著差异。进行了成本最小化分析,以比较CBA与RFA的医疗成本,因为两种手术之间的AF复发风险没有显着差异。CBA和RFA的估计成本为4858544日元(32390美元)和4505255日元(30035美元),分别,RFA的成本节约为353289日元(2355美元)。
■我们的荟萃分析表明,与RFA相比,CBA在房颤复发方面具有相当的益处。如以前的研究所示。尽管治疗的选择应根据患者和治疗特点,RFA显示,与CBA相比,它可能节省成本。