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Abstract：
UNASSIGNED: To explore the efficiency and safety of carbon dioxide (CO2) laser-assisted sclerectomy surgery (CLASS) in Chinese patients with glaucoma secondary to vitrectomy.
UNASSIGNED: This retrospective study consisted of 16 eyes from 16 patients with glaucoma secondary to vitrectomy who underwent CLASS and were followed up for 12 months. Main outcome measures included preoperative and postoperative intraocular pressure, best corrected visual acuity (BCVA), number of anti-glaucoma medications, and postoperative surgical success rate and complications.
UNASSIGNED: The postoperative IOP and number of anti-glaucoma medications used at all follow-up time point were significantly lower than those preoperatively. The difference in BCVA was not significant before and after surgery. The main complicatios were peripheral anterior synechiae (PAS) and scleral reservoir reduction, which were controlled after neodymium-doped yttrium aluminum garnet (Nd:YAG) laser, 2 (12.50%) patients underwent re-operation. The complete and total success rates at 12 months were 68.75% and 87.50%, respectively.
UNASSIGNED: CLASS is a safe and effective procedure for Chinese patients with glaucoma secondary to vitrectomy. PAS and scleral reservoir reduction is a major contributor to postoperative IOP elevation, and trabecular minimally invasive perforation with the Nd:YAG laser is effective in lowering IOP and increasing scleral cistern volume.
UNASSIGNED: This retrospective study consisted of 16 eyes from 16 patients with glaucoma secondary to vitrectomy who underwent CLASS and were followed up for 12 months. Main outcome measures included preoperative and postoperative intraocular pressure, best corrected visual acuity (BCVA), number of anti-glaucoma medications, and postoperative surgical success rate and complications.
UNASSIGNED: The postoperative IOP and number of anti-glaucoma medications used at all follow-up time point were significantly lower than those preoperatively. The difference in BCVA was not significant before and after surgery. The main complicatios were peripheral anterior synechiae (PAS) and scleral reservoir reduction, which were controlled after neodymium-doped yttrium aluminum garnet (Nd:YAG) laser, 2 (12.50%) patients underwent re-operation. The complete and total success rates at 12 months were 68.75% and 87.50%, respectively.
UNASSIGNED: CLASS is a safe and effective procedure for Chinese patients with glaucoma secondary to vitrectomy. PAS and scleral reservoir reduction is a major contributor to postoperative IOP elevation, and trabecular minimally invasive perforation with the Nd:YAG laser is effective in lowering IOP and increasing scleral cistern volume.
摘要：
■探讨二氧化碳（CO2）激光辅助巩膜切除术（CLASS）在中国玻璃体切除术继发青光眼患者中的有效性和安全性。
■这项回顾性研究包括16例玻璃体切除术继发青光眼患者的16只眼，这些患者接受了CLASS并随访了12个月。主要结局指标包括术前和术后眼压，最佳矫正视力（BCVA），抗青光眼药物的数量，术后手术成功率和并发症。
■术后眼压和所有随访时间点使用的抗青光眼药物数量均明显低于术前。手术前后BCVA差异无统计学意义。主要并发症是外周前粘连（PAS）和巩膜储层减少，在掺钕钇铝石榴石（Nd：YAG）激光后进行控制，2例(12.50%)患者行再次手术。12个月的完全成功率和总成功率分别为68.75%和87.50%,分别。
■CLASS是一种安全有效的方法，适用于玻璃体切除术继发青光眼的中国患者。PAS和巩膜储层减少是术后IOP升高的主要原因，Nd：YAG激光小梁微创穿孔可有效降低眼压，增加巩膜池体积。
■这项回顾性研究包括16例玻璃体切除术继发青光眼患者的16只眼，这些患者接受了CLASS并随访了12个月。主要结局指标包括术前和术后眼压，最佳矫正视力（BCVA），抗青光眼药物的数量，术后手术成功率和并发症。
■术后眼压和所有随访时间点使用的抗青光眼药物数量均明显低于术前。手术前后BCVA差异无统计学意义。主要并发症是外周前粘连（PAS）和巩膜储层减少，在掺钕钇铝石榴石（Nd：YAG）激光后进行控制，2例(12.50%)患者行再次手术。12个月的完全成功率和总成功率分别为68.75%和87.50%,分别。
■CLASS是一种安全有效的方法，适用于玻璃体切除术继发青光眼的中国患者。PAS和巩膜储层减少是术后IOP升高的主要原因，Nd：YAG激光小梁微创穿孔可有效降低眼压，增加巩膜池体积。
