关键词: cataract surgery dry eye inflammatory cytokines lipiflow (thermal pulsation) meibomian gland

来  源:   DOI:10.2147/OPTH.S459472   PDF(Pubmed)

Abstract:
UNASSIGNED: The aim of the current study was to investigate the efficacy of Thermal pulsation treatment, completed one month prior to cataract surgery, as a means of eliminating or significantly mitigating the exacerbating effects of cataract surgery on dry eye patients.
UNASSIGNED: Glendale, Arizona.
UNASSIGNED: Prospective, longitudinal, non-masked, randomized clinical investigation.
UNASSIGNED: The treatment group received Thermal pulsation therapy approximately 1 month prior to undergoing immediate sequential, same-day bilateral cataract surgery. The control group did not receive pre-operative Thermal pulsation but had cataract surgery performed in the same way, approximately 1 month after their baseline visit. Subjective questionnaires and objective clinical findings were evaluated at baseline, 1, 3, and 6 months after cataract surgery in the treatment group and control group.
UNASSIGNED: A total of 62 patients were randomized into two groups of 31 representing 124 eyes. Subjective improvement was observed in the treatment group with OSDI and SPEED II scores. Mean (SD) of the OSDI improved significantly (p<0.01) from 56.98 (18.30) from visit 1 to 14.73 (12.22) at visit 4, and the mean (SD) of the SPEED II scores improved significantly (p=0.01) from 13.84 (6.12) during visit 1 to 7.1 (5.00) at visit 4 in the treatment group.
UNASSIGNED: Pre-operative Thermal pulsation treatment in patients with dry eye secondary to MGD appears to reduce dry eye symptoms after cataract surgery. Expectations should be moderated by the fact that the reduction in symptoms appears to reduce prior to 3 months post-op after cataract surgery.
摘要:
当前研究的目的是调查热脉动治疗的疗效,在白内障手术前一个月完成,作为消除或显著减轻白内障手术对干眼患者的恶化影响的手段。
格伦代尔,亚利桑那.
预期,纵向,非蒙面,随机临床调查。
治疗组在立即进行序贯治疗前约1个月接受热搏动治疗,当天双侧白内障手术。对照组不接受术前热脉动,但以相同的方式进行了白内障手术。大约1个月后,他们的基线访问。在基线时评估主观问卷和客观临床结果,治疗组与对照组分别于白内障术后1、3、6个月进行治疗。
总共62名患者被随机分为两组,每组31只,代表124只眼。在OSDI和SPEEDII评分的治疗组中观察到主观改善。OSDI的平均值(SD)从第1次就诊的56.98(18.30)显着提高(p<0.01)到第4次就诊的14.73(12.22),并且SPEEDII评分的平均值(SD)显着提高(p=0.01)从第1次就诊的13.84(6.12)到第4次就诊的7.1(5.00)。
对MGD继发干眼患者的术前热脉动治疗似乎可以减轻白内障手术后的干眼症状。在白内障手术后3个月之前,症状的减轻似乎减轻了,这一事实应使期望得到缓解。
公众号