PDF(Pubmed)
Abstract：
UNASSIGNED: Non-tuberculous mycobacteria (NTM) are a group of mycobacteria that are commonly found in the environment and can cause disease in humans. The symptoms of NTM infection can be similar to those of tuberculosis, making diagnosis challenging. The morbidity associated with NTM is increasing, and clinical management can be challenging.
UNASSIGNED: This report details the case of a 32-year-old male who was found to have multiple enlarged and partially necrotic lymph nodes in the neck, axilla, mediastinum, and retroperitoneum. The causative agent was rapidly identified as Mycobacterium paracondontium through pathogen-targeted sequencing (tNGS). After two weeks of treatment with azithromycin, moxifloxacin, rifabutin, and amikacin, the patient\'s uncomfortable symptoms had resolved, and he is currently undergoing further review.
UNASSIGNED: It is imperative that clinicians remain vigilant for the presence of NTM, particularly those that are rare, given their pervasiveness in the environment. Prompt diagnosis is of paramount importance, and molecular identification techniques represent a crucial tool in this regard. In vitro drug sensitivity testing should be conducted whenever feasible to guarantee the administration of an efficacious treatment regimen.
UNASSIGNED: This report details the case of a 32-year-old male who was found to have multiple enlarged and partially necrotic lymph nodes in the neck, axilla, mediastinum, and retroperitoneum. The causative agent was rapidly identified as Mycobacterium paracondontium through pathogen-targeted sequencing (tNGS). After two weeks of treatment with azithromycin, moxifloxacin, rifabutin, and amikacin, the patient\'s uncomfortable symptoms had resolved, and he is currently undergoing further review.
UNASSIGNED: It is imperative that clinicians remain vigilant for the presence of NTM, particularly those that are rare, given their pervasiveness in the environment. Prompt diagnosis is of paramount importance, and molecular identification techniques represent a crucial tool in this regard. In vitro drug sensitivity testing should be conducted whenever feasible to guarantee the administration of an efficacious treatment regimen.
摘要：
■非结核分枝杆菌（NTM）是一组在环境中常见的分枝杆菌，可在人类中引起疾病。NTM感染的症状可能与结核病相似，诊断具有挑战性。与NTM相关的发病率正在增加，和临床管理可能是具有挑战性的。
本报告详述了一名32岁男性的病例，他被发现颈部有多个肿大和部分坏死的淋巴结，腋下,纵隔,和腹膜后.通过病原体靶向测序（tNGS），可以将病原体快速鉴定为副核分枝杆菌。阿奇霉素治疗两周后，莫西沙星,rifabutin,和阿米卡星,病人的不适症状已经解决，他目前正在接受进一步审查。
■临床医生必须对NTM的存在保持警惕，尤其是那些罕见的，考虑到他们在环境中的普遍性。及时诊断至关重要，和分子鉴定技术在这方面是一个至关重要的工具。在可行的情况下，应进行体外药物敏感性测试，以确保有效的治疗方案。
本报告详述了一名32岁男性的病例，他被发现颈部有多个肿大和部分坏死的淋巴结，腋下,纵隔,和腹膜后.通过病原体靶向测序（tNGS），可以将病原体快速鉴定为副核分枝杆菌。阿奇霉素治疗两周后，莫西沙星,rifabutin,和阿米卡星,病人的不适症状已经解决，他目前正在接受进一步审查。
■临床医生必须对NTM的存在保持警惕，尤其是那些罕见的，考虑到他们在环境中的普遍性。及时诊断至关重要，和分子鉴定技术在这方面是一个至关重要的工具。在可行的情况下，应进行体外药物敏感性测试，以确保有效的治疗方案。
