Abstract：
UNASSIGNED: Parkinson\'s Disease (PD) is a progressive, chronic neurodegenerative disease, representing significant economic and social burdens. It is typically defined by motor symptoms (MSs), however, this does not reflect the full patient burden. Non-motor symptoms (NMSs) are increasingly recognized as central characteristics of PD. However, they still lack recognition in research. Therefore, this study aims to identify relevant NMSs, their prevalence, and the effect they have on Quality-of-Life (QoL) and Cost-of-Illness (COI). Secondly, it aims to identify gaps in the current body of knowledge and propose possible ways future research could bridge those gaps.
UNASSIGNED: The study employed a scoping review, identifying 60 records for inclusion, using PubMed and Web of Science. It included studies from Spain or Italy, including data on People with Parkinson\'s Disease. A comparative analysis was performed using Microsoft Excel.
UNASSIGNED: It showed that the body of evidence relevant to NMSs, their prevalence, QoL, and COI is limited, or that estimates vary to an extent where interpretation is difficult.
UNASSIGNED: Most studies suffer from generalization, representation, and standardization issues, stemming from their designs and methodological decisions. Although the findings of this study should be interpreted with caution, several recommendations are made for future research.
UNASSIGNED: The study employed a scoping review, identifying 60 records for inclusion, using PubMed and Web of Science. It included studies from Spain or Italy, including data on People with Parkinson\'s Disease. A comparative analysis was performed using Microsoft Excel.
UNASSIGNED: It showed that the body of evidence relevant to NMSs, their prevalence, QoL, and COI is limited, or that estimates vary to an extent where interpretation is difficult.
UNASSIGNED: Most studies suffer from generalization, representation, and standardization issues, stemming from their designs and methodological decisions. Although the findings of this study should be interpreted with caution, several recommendations are made for future research.
摘要：
■帕金森病(PD)是一种进行性、慢性神经退行性疾病，代表着巨大的经济和社会负担。它通常由运动症状(MS)定义，然而,这并不能反映患者的全部负担。非运动症状（NMS）越来越被认为是PD的主要特征。尽管最近的事态发展,NMS在患者和临床医生的研究中仍然缺乏认可，可能导致错误的诊断和治疗.因此,这项研究采用了范围审查来确定相关的NMS，他们的患病率，以及它们对生活质量(QoL)和疾病成本(COI)的影响。其次,这项研究旨在确定当前围绕PDNMS的知识体系中的差距，并提出未来研究可以弥合这些差距的可能方法。
■此范围审查确定了60条记录，使用PubMed和WebofScience。它包括来自西班牙或意大利的研究，包括帕金森病患者的数据。使用MicrosoftExcel进行比较分析。
■它表明与NMS相关的证据，他们的患病率，QoL,和COI是有限的，或者估计在解释困难的程度上有所不同。
■大多数研究都受到泛化的影响，representation,和标准化问题，源于他们的设计和方法决策。尽管由于范围审查设计，本研究的结果应谨慎解释，对未来的研究提出了一些建议，以产生更可靠的数据。
■此范围审查确定了60条记录，使用PubMed和WebofScience。它包括来自西班牙或意大利的研究，包括帕金森病患者的数据。使用MicrosoftExcel进行比较分析。
■它表明与NMS相关的证据，他们的患病率，QoL,和COI是有限的，或者估计在解释困难的程度上有所不同。
■大多数研究都受到泛化的影响，representation,和标准化问题，源于他们的设计和方法决策。尽管由于范围审查设计，本研究的结果应谨慎解释，对未来的研究提出了一些建议，以产生更可靠的数据。
