METHODS: Women presenting for breast imaging during 2 weeks in 2023 were surveyed. Thirty-five patients with a history or diagnosis of BC were excluded. The Tyrer-Cuzick (TC) model version 8 was used to calculate BC risk. High/intermediate risk was defined as a 10-year risk of 5% or more, a lifetime risk of 15% or more, or both. The criteria for genetic counseling and testing referral were based on National Comprehensive Cancer Network guidelines.
RESULTS: A total of 257 patients had a TC risk assessment showing 14.8% (n = 38) with a 10-year BC risk of 5% or more (consideration of endocrine therapy), 6.2% (n = 16) with a lifetime BC risk of 20% or more (qualifying for annual screening MRI), and 10.5% (n = 27) with a lifetime BC risk of 15% or more (consideration of high-risk screening). The criteria for genetic counseling/testing were met by 61 (23.7%) of the 257 patients. Overall, 31.5% (n = 81) qualified for high/intermediate-risk screening, risk reduction, and/or genetic assessment/testing, 92.8% of whom were interested in referrals for additional information and care.
CONCLUSIONS: In the authors\' community, almost one third of patients undergoing breast imaging qualify for BC high-risk assessment and services. The majority of the patients expressed interest in pursuing such services. These data will be used in financial planning and resource allocation to develop a high-risk program at the authors\' institution in line with NAPBC guidelines. They are hopeful that these efforts will improve oncologic outcomes and survival from BC in their community.
方法:调查了2023年在2周内进行乳腺成像的女性。排除了35例有BC病史或诊断的患者。Tyrer-Cuzick(TC)模型版本8用于计算BC风险。高/中风险被定义为5%或以上的10年风险,一生的风险为15%或更高,或者两者兼而有之。遗传咨询和检测转诊的标准基于国家综合癌症网络指南。
结果:总共257例患者的TC风险评估显示14.8%(n=38),10年BC风险为5%或更高(考虑内分泌治疗),6.2%(n=16),终生BC风险为20%或更高(符合年度MRI筛查要求),和10.5%(n=27),终生BC风险为15%或更高(考虑高风险筛查)。257名患者中有61名(23.7%)符合遗传咨询/检测标准。总的来说,31.5%(n=81)符合高/中风险筛查,降低风险,和/或基因评估/测试,其中92.8%的人对转介其他信息和护理感兴趣。
结论:在作者社区中,近三分之一接受乳腺成像的患者符合BC高危评估和服务的条件.大多数患者表示有兴趣寻求此类服务。这些数据将用于财务规划和资源分配,以根据NAPBC指南在作者机构制定高风险计划。他们希望这些努力将改善BC社区的肿瘤学结果和生存率。