Abstract：
Objectives: We aimed to investigate the mediating role of lifestyle activities in the association between social deprivation and cognition. Methods: To investigate, we analysed data of 3867 respondents (Mean Age: 73.37, SD: 5.57) in the U.S. Health and Retirement Study (HRS) using growth curve and path analysis, adjusted for demographic and health covariates. Results: Being in the high (vs. moderate) Social Deprivation Index group was associated with lower cognition scores (β = -2.63, [95 % CI: -2.90, -2.36]). Conversely, higher (vs. lower) Lifestyle Index scores were associated with higher cognition scores (β = 1.17, [95 % CI: 0.72, 1.63]). In mediation analysis, the Lifestyle Index score explained 27 % of the association of So Dep Index group on cognition at the final follow-up. Discussion: While lifestyle activities did mediate the association between social deprivation and cognition, factors not investigated accounted for the majority of the variation. These may include systemic disadvantages.
摘要：
目的：我们旨在探讨生活方式活动在社会剥夺与认知之间的中介作用。方法:调查,我们使用增长曲线和路径分析分析了美国健康与退休研究（HRS）中3867名受访者（平均年龄：73.37，SD：5.57）的数据，根据人口统计学和健康协变量进行调整。结果：处于高位(vs.中度）社会剥夺指数组的认知得分较低（β=-2.63，[95％CI：-2.90，-2.36]）。相反，更高(vs.较低）生活方式指数得分与较高的认知得分相关（β=1.17，[95%CI：0.72，1.63]）。在调解分析中，生活方式指数评分解释了SoDep指数组与最终随访时认知相关的27%。讨论：虽然生活方式活动确实调解了社会剥夺和认知之间的联系，未调查的因素占了变异的大部分。这些可能包括系统性缺点。
