Mesh : Humans Anesthesia, General / adverse effects Parkinson Disease / drug therapy Antiparkinson Agents / adverse effects therapeutic use Male Aged Syndrome Female Parkinsonian Disorders / etiology

来  源:   DOI:10.1213/XAA.0000000000001840

Abstract:
Parkinsonism-hyperpyrexia syndrome (PHS) is a rare, fatal complication of Parkinson\'s disease (PD) that manifests in patients who abruptly discontinue or reduce their antiParkinsonian medication. To the best of our knowledge, this is the first report of a PHS case occurring in a patient undergoing general anesthesia. In the perioperative period of PD patients, it is important for anesthesiologists to prevent PHS as well as monitor patients to enable early detection and prompt response when it occurs.
摘要:
帕金森综合征-高热综合征(PHS)是一种罕见的,帕金森病(PD)的致命并发症,表现在突然停止或减少抗帕金森病药物治疗的患者。据我们所知,这是在接受全身麻醉的患者中发生的PHS病例的首例报告.在PD患者的围手术期,对于麻醉医师来说,预防PHS并对患者进行监测,以便在发生PHS时能够早期发现并迅速作出反应是非常重要的.
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