Abstract：
As the role of neurologists in managing patients with rheumatic diseases expands, collaboration between rheumatologists and neurologists becomes increasingly vital. This literature review provides an overview of the central nervous system (CNS) manifestations of major autoimmune rheumatic disorders, which may include parenchymal brain and meningeal disease (stroke, meningoencephalitis, meningitis), myelopathies, psychosis, chorea, seizure disorders, and various forms of cephalea. Novel findings linking specific autoimmune markers to CNS damage reveal a direct, previously underestimated link between systemic inflammation and neural injury. Besides, with the increasing use of biological therapies, it is crucial to recognize when neurological manifestations are related to adverse events of therapy, as this may significantly influence treatment decisions. Neurologists play a key role in this assessment, working closely with rheumatologists. Overall, addressing CNS involvement in rheumatic diseases is important for improving patient outcomes and advancing medical knowledge in this complex field. A thorough understanding of the neurologic aspects of rheumatic diseases is essential for optimal patient care, necessitating a multidisciplinary approach to management.
摘要：
随着神经科医生在风湿性疾病患者管理中的作用不断扩大，风湿病学家和神经学家之间的合作变得越来越重要。这篇文献综述概述了主要自身免疫性风湿性疾病的中枢神经系统（CNS）表现，可能包括脑实质和脑膜疾病（中风，脑膜脑炎,脑膜炎)，脊髓病,精神病,舞蹈病,癫痫症,和各种形式的头颅。将特定的自身免疫标志物与中枢神经系统损伤联系起来的新发现揭示了一种直接的,以前低估了全身炎症和神经损伤之间的联系。此外,随着越来越多地使用生物疗法，至关重要的是要认识到何时神经系统表现与治疗不良事件有关，因为这可能会显著影响治疗决策。神经学家在这项评估中起着关键作用，与风湿病学家密切合作。总的来说,解决中枢神经系统参与风湿性疾病对改善患者预后和提高这一复杂领域的医学知识很重要。彻底了解风湿性疾病的神经系统方面对于最佳的患者护理至关重要。需要多学科的管理方法。
