Abstract：
Novel surgical treatments for painful neuromas are increasingly used, but determining which provides the greatest benefit has been difficult due to the inconsistent use of outcome measures. We mapped the current literature of outcome measures used to evaluate peripheral nerve surgery for the management of symptomatic neuromas in patients who underwent an adult-acquired upper extremity amputation (UEA). Medline, Embase, Cochrane, and CINAHL were searched for primary research written in the English language from inception to February 2023. The search yielded 1137 articles, of which 35 were included for final analysis. Studies varied in their assessment of pain, health-related quality of life (HRQOL), neurotrophic measures, psychological and sensorimotor function, highlighting a consensus on crucial domains but also revealing significant heterogeneity in the use and application of outcome measures among primary studies. Our findings highlight the need to establish common standards that reflect the best evidence and unique needs of the UEA population. This includes developing a core outcome set, utilizing multi-center trials, and maintaining flexibility to adapt to ongoing advancements in patient-reported outcome measures (PROMs) research.
摘要：
疼痛性神经瘤的新型手术治疗方法越来越多地被使用，但是，由于结果衡量标准的使用不一致，很难确定哪种获益最大。我们绘制了用于评估周围神经手术治疗成人获得性上肢截肢（UEA）患者症状性神经瘤的结局指标的最新文献。Medline,Embase,科克伦,从成立之初到2023年2月，我们对和CINAHL进行了搜索，以获得以英语编写的主要研究。搜索产生了1137篇文章，其中35个被列入最终分析。研究对疼痛的评估各不相同，健康相关生活质量（HRQOL），神经营养措施，心理和感觉运动功能，强调在关键领域的共识，但也揭示了主要研究中结果指标的使用和应用的显着异质性。我们的发现强调了建立反映UEA人群最佳证据和独特需求的共同标准的必要性。这包括制定核心成果集，利用多中心试验，并保持灵活性以适应患者报告结果测量（PROMs）研究的持续进步。
