关键词: Thyroid neck mass neuroendocrine tumor paraganglioma

来  源:   DOI:10.1080/00015458.2024.2392349

Abstract:
UNASSIGNED: Thyroid-originated paragangliomas are very uncommon, and there is a lack of established guidelines regarding their management.
UNASSIGNED: A case study was presented, and a review of the literature was conducted.
UNASSIGNED: Diagnosing a paraganglioma requires multiple diagnostic methods, including a 24-h measurement of metanephrines or catecholamines, anatomical imaging using magnetic resonance or computed tomography (CT) scans, and functional imaging using metaiodobenzylguanidine or 18F-DOPA PET/CT scans. Additionally, with the presence of somatostatin receptors on paragangliomas, the use of octreotide scans such as a 68Ga DOTATATE PET/CT scan is expected to increase soon. The primary treatment for laryngeal paragangliomas is surgical intervention aimed at achieving optimal tumor removal while retaining the highest possible level of laryngeal function. One should not do elective neck dissection given the low risk of metastasis and recurrence. Although the rate of recurrence and metastasis for paragangliomas is low, continued monitoring through clinic visits, biochemical testing, and imaging is still necessary. Furthermore, follow-up efforts should also consider genetic testing of the critical genes associated with paragangliomas.
UNASSIGNED: Although there is still debate regarding the existence of thyroid paraganglioma, it can nonetheless be classified as a subtype of laryngeal paragangliomas. All hypervascular thyroid nodules require the consideration of thyroid-associated paragangliomas.
摘要:
甲状腺起源的副神经节瘤非常罕见,并且缺乏有关其管理的既定准则。
提出了一个案例研究,并对文献进行了回顾。
诊断副神经节瘤需要多种诊断方法,包括24小时测量间肾上腺素或儿茶酚胺,使用MR或CT扫描的解剖成像,和使用MIBG或18F-DOPAPET/CT扫描的功能成像。此外,副神经节瘤上存在生长抑素受体,奥曲肽扫描如68GaDOTATATEPET/CT扫描的使用预计将很快增加.喉副神经节瘤的主要治疗方法是手术干预,旨在实现最佳的肿瘤切除,同时保留尽可能高的喉功能水平。鉴于转移和复发的风险较低,不应进行选择性颈淋巴结清扫术。尽管副神经节瘤的复发率和转移率很低,通过诊所访问继续监测,生化检测,成像仍然是必要的。此外,后续工作还应考虑对与副神经节瘤相关的关键基因进行基因检测.
尽管关于甲状腺副神经节瘤的存在仍存在争议,尽管如此,它仍可以归类为喉神经节旁瘤的亚型。所有高血管甲状腺结节都需要考虑甲状腺相关的副神经节瘤。
公众号