PDF(Pubmed)
Abstract：
UNASSIGNED: Nanovaccine treatment is an exciting area of research in immunology and personalized medicine, holding great promise for enhancing immune responses and targeting specific diseases. Their small size allows efficient uptake by immune cells, leading to robust immune activation. They can incorporate immune-stimulating molecules to boost vaccine efficacy. Therefore, nanovaccine can be personalized to target tumor-specific antigens, activating the immune system against cancer cells. Currently, there have been ample evidence showing the effectiveness and potential of nanovaccine as a treatment for cancer. However, there was rare bibliometric analysis of nanovaccine for cancer. Here we performed a bibliometric and visual analysis of published studies related to nanovaccine treatment for cancer, providing the trend of future development of nanovaccine.
UNASSIGNED: We collected the literatures based on the Web of Science Core Collection SCI-Expanded database. The bibliometric analysis was performed via utilizing visualization analysis tools VOSviewer, Co-Occurrence (COOC), Citespace, Bibliometrix (R-Tool of R-Studio), and HitCite.
UNASSIGNED: A total of 517 literatures were included in this study. China is the country with the most publications and the highest total local citation score (TLCS). The Chinese Academy of Sciences holds the largest research count in this field and the most prolific author is Deling Kong from Nankai University. The most prominent journal for publishing in this area is Biomaterials. The researches mainly focus on the therapeutic process of tumor nanovaccines, the particle composition and the application of nanovaccines, suggesting the potential hotspots and trends of nanovaccine.
UNASSIGNED: In this study, we summarized the characteristics and variation trends of publications involved in nanovaccine, and categorized the most influential countries, institutions, authors, journals, hotspots and trends regarding the nanovaccine for cancer. With the continuous development of nanomaterials and tumor immunotherapy, nanovaccine for cancer provides a research field of significant clinical value and potential application.
UNASSIGNED: We collected the literatures based on the Web of Science Core Collection SCI-Expanded database. The bibliometric analysis was performed via utilizing visualization analysis tools VOSviewer, Co-Occurrence (COOC), Citespace, Bibliometrix (R-Tool of R-Studio), and HitCite.
UNASSIGNED: A total of 517 literatures were included in this study. China is the country with the most publications and the highest total local citation score (TLCS). The Chinese Academy of Sciences holds the largest research count in this field and the most prolific author is Deling Kong from Nankai University. The most prominent journal for publishing in this area is Biomaterials. The researches mainly focus on the therapeutic process of tumor nanovaccines, the particle composition and the application of nanovaccines, suggesting the potential hotspots and trends of nanovaccine.
UNASSIGNED: In this study, we summarized the characteristics and variation trends of publications involved in nanovaccine, and categorized the most influential countries, institutions, authors, journals, hotspots and trends regarding the nanovaccine for cancer. With the continuous development of nanomaterials and tumor immunotherapy, nanovaccine for cancer provides a research field of significant clinical value and potential application.
摘要：
■纳米疫苗治疗是免疫学和个性化医学研究的一个令人兴奋的领域，在增强免疫反应和针对特定疾病方面有着巨大的希望。它们的小尺寸允许免疫细胞有效吸收，导致强大的免疫激活。它们可以掺入免疫刺激分子以提高疫苗效力。因此,纳米疫苗可以个性化靶向肿瘤特异性抗原，激活免疫系统对抗癌细胞。目前,有充分的证据表明纳米疫苗作为癌症治疗的有效性和潜力。然而,有罕见的癌症纳米疫苗的文献计量学分析。在这里，我们对已发表的与纳米疫苗治疗癌症相关的研究进行了文献计量和视觉分析，未来纳米疫苗的发展趋势。
■我们收集了基于WebofScienceCoreCollectionSCI扩展数据库的文献。文献计量分析是通过利用可视化分析工具VOSviewer进行的，共同发生(COOC)，城市空间,Bibliometrix(R-ToolofR-Studio),还有Hitcite.
■本研究共纳入517篇文献。中国是出版物最多的国家，也是当地引文总分（TLCS）最高的国家。中国科学院拥有该领域最大的研究数量，最多产的作者是南开大学的德令孔。该领域最著名的期刊是生物材料。研究主要集中在肿瘤纳米疫苗的治疗过程,纳米疫苗的颗粒组成和应用，提示纳米疫苗的潜在热点和趋势。
■在这项研究中，我们总结了涉及纳米疫苗的出版物的特征和变化趋势，并对最具影响力的国家进行了分类，机构,作者,期刊,关于癌症纳米疫苗的热点和趋势。随着纳米材料和肿瘤免疫治疗技术的不断发展,纳米疫苗为癌症提供了一个具有重要临床价值和潜在应用的研究领域。
■我们收集了基于WebofScienceCoreCollectionSCI扩展数据库的文献。文献计量分析是通过利用可视化分析工具VOSviewer进行的，共同发生(COOC)，城市空间,Bibliometrix(R-ToolofR-Studio),还有Hitcite.
■本研究共纳入517篇文献。中国是出版物最多的国家，也是当地引文总分（TLCS）最高的国家。中国科学院拥有该领域最大的研究数量，最多产的作者是南开大学的德令孔。该领域最著名的期刊是生物材料。研究主要集中在肿瘤纳米疫苗的治疗过程,纳米疫苗的颗粒组成和应用，提示纳米疫苗的潜在热点和趋势。
■在这项研究中，我们总结了涉及纳米疫苗的出版物的特征和变化趋势，并对最具影响力的国家进行了分类，机构,作者,期刊,关于癌症纳米疫苗的热点和趋势。随着纳米材料和肿瘤免疫治疗技术的不断发展,纳米疫苗为癌症提供了一个具有重要临床价值和潜在应用的研究领域。
