关键词: Bipolar disorder DYMERS MDQ New syndrome Rhythm dysregulation SLE

来  源:   DOI:10.2174/0117450179303653240705051227   PDF(Pubmed)

Abstract:
UNASSIGNED: This study explores the issue of paper-and-pencil screening tests for bipolar disorder, often leading to false positives. It discusses hypotheses that connect MDQ positivity with sleep disorders, a decline in health-related quality of life, and the impact of the COVID-19 pandemic on mood disorders. The study proposes that MDQ identifies a \"Dysregulation of Mood, Energy, and Social Rhythms Syndrome\" (DYMERS), indicating a stress-related condition. It aims to investigate the association between MDQ positivity and systemic lupus erythematosus (SLE) in comparison to other chronic disorders.
UNASSIGNED: This case-control study, conducted from April 2019 to February 2020, investigated MDQ positivity in patients with SLE. Ethical approvals were obtained, and statistical analysis was used for data assessment.
UNASSIGNED: This is a case-controlled study where MDQ positivity was significantly higher in systemic lupus erythematosus cases than controls. The analysis compared gender, age, and the presence of depressive episodes between MDQ-positive and MDQ-negative cases, revealing some differences but no significant variations. Interestingly, no association with high prednisone or biologics use was observed. The frequency of MDQ positivity in systemic lupus erythematosus was compared to other chronic pathologies, revealing varying associations with each condition.
UNASSIGNED: This study reveals a high rate of (MDQ) positivity in systemic lupus erythematosus (SLE), associated with the risk of bipolar disorder in SLE. Notable discrepancies in MDQ positivity risk factors between SLE and bipolar disorder are observed. The study emphasizes the ability of MDQ to identify a distinct syndrome characterized by rhythm dysregulation, posing a risk for bipolar disorder and other disorders.
摘要:
这项研究探讨了双相情感障碍的纸笔筛查测试的问题,经常导致误报。它讨论了将MDQ阳性与睡眠障碍联系起来的假设,与健康相关的生活质量下降,以及COVID-19大流行对情绪障碍的影响。这项研究提出,MDQ识别出情绪失调,能源,和社会节律综合征(DYMERS),表明与压力相关的状况。与其他慢性疾病相比,旨在研究MDQ阳性与系统性红斑狼疮(SLE)之间的关联。
本病例对照研究,从2019年4月至2020年2月进行,调查了SLE患者的MDQ阳性。获得了道德批准,并采用统计学分析进行数据评估。
这是一项病例对照研究,其中系统性红斑狼疮病例的MDQ阳性明显高于对照组。分析比较了性别,年龄,以及MDQ阳性和MDQ阴性病例之间存在抑郁发作,揭示了一些差异,但没有显著的变化。有趣的是,未观察到与高泼尼松或生物制剂使用相关.将系统性红斑狼疮中MDQ阳性的频率与其他慢性病理进行比较,揭示与每个条件的不同关联。
这项研究揭示了系统性红斑狼疮(SLE)的高(MDQ)阳性率,与SLE患者双相情感障碍的风险相关。观察到SLE和双相情感障碍之间MDQ阳性危险因素的显着差异。该研究强调了MDQ识别以节律失调为特征的独特综合征的能力。构成双相情感障碍和其他疾病的风险。
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