PDF(Pubmed)
Abstract：
The human gut microbiome (GM) impacts various physiological processes and can lead to pathological conditions and even carcinogenesis if homeostasis is disrupted. Recent studies have indicated a connection between the GM and prostatic disease. However, the underlying mechanisms are still unclear. This review aims to provide a summary of the existing information regarding the connection between the GM and various prostatic conditions such as chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS), benign prostatic hyperplasia (BPH), and prostate cancer (PCa). Furthermore, the review aims to identify possible pathogenic mechanisms and suggest potential ways of targeting GM to prevent and treat prostatic disease. Due to the complexity of the mechanism between GM and prostatic diseases, additional research is required to comprehend the association between the two. This will lead to more effective treatment options for prostatic disease.
摘要：
人类肠道微生物组（GM）影响各种生理过程，如果稳态被破坏，可能导致病理状况甚至致癌作用。最近的研究表明，GM与前列腺疾病之间存在联系。然而,潜在机制尚不清楚.这篇综述旨在提供有关GM与各种前列腺疾病如慢性前列腺炎/慢性盆腔疼痛综合征（CP/CPPS）之间联系的现有信息的摘要。良性前列腺增生(BPH),前列腺癌（PCa）。此外，本综述旨在确定可能的致病机制,并提出靶向GM预防和治疗前列腺疾病的潜在方法.由于GM和前列腺疾病之间的机制的复杂性，需要更多的研究来理解两者之间的联系。这将为前列腺疾病带来更有效的治疗选择。
