PDF(Pubmed)
Abstract：
BACKGROUND: Foot drop in people with multiple sclerosis (MS) commonly leads to decreased mobility and quality of life (QOL). Functional electrical stimulation (FES) of the peroneal nerve can improve the gait of people with foot drop, yet various barriers restrict widespread use. The purpose of this case series was to examine the feasibility of a telerehabilitation-monitored FES device and report changes in functional mobility and QOL in people with moderate MS-related disability.
METHODS: FES use was progressed over 8 weeks via 3 telerehabilitation sessions. Feasibility of telerehabilitation was assessed by percentage of telerehabilitation visits completed and participant-reported satisfaction. At baseline and study completion, functional mobility with and without FES were assessed by the Timed 25-Foot Walk (T25FW), Timed Up and Go (TUG), and 2-Minute Walk Test (2MWT), Multiple Sclerosis Impact Scale (MSIS-29), and the 12-item Multiple Sclerosis Walking Scale (MSWS-12). Fatigue was assessed via the Modified Fatigue Impact Scale (MFIS) before and after the intervention.
RESULTS: Eleven participants (mean age = 50.4 years [SD 10.8]; 2 males) completed the study. All (33/33) telerehabilitation visits were completed and participants attained high levels of satisfaction with no adverse events. At 8 weeks, compared to baseline, there were clinically meaningful improvements on the T25FW, 2MWT, and TUG for 45%, 55%, and 82% of participants, respectively. Clinically meaningful improvements on the MSIS-29 and MSWS-12 were also recorded for 64% and 36% of participants, respectively.
CONCLUSIONS: Telerehabilitation was safe and feasible for FES intervention, and improvements in functional mobility and QOL were observed. Telerehabilitation to monitor FES may improve access and reduce patient burden; therefore, studying its efficacy is warranted.
METHODS: FES use was progressed over 8 weeks via 3 telerehabilitation sessions. Feasibility of telerehabilitation was assessed by percentage of telerehabilitation visits completed and participant-reported satisfaction. At baseline and study completion, functional mobility with and without FES were assessed by the Timed 25-Foot Walk (T25FW), Timed Up and Go (TUG), and 2-Minute Walk Test (2MWT), Multiple Sclerosis Impact Scale (MSIS-29), and the 12-item Multiple Sclerosis Walking Scale (MSWS-12). Fatigue was assessed via the Modified Fatigue Impact Scale (MFIS) before and after the intervention.
RESULTS: Eleven participants (mean age = 50.4 years [SD 10.8]; 2 males) completed the study. All (33/33) telerehabilitation visits were completed and participants attained high levels of satisfaction with no adverse events. At 8 weeks, compared to baseline, there were clinically meaningful improvements on the T25FW, 2MWT, and TUG for 45%, 55%, and 82% of participants, respectively. Clinically meaningful improvements on the MSIS-29 and MSWS-12 were also recorded for 64% and 36% of participants, respectively.
CONCLUSIONS: Telerehabilitation was safe and feasible for FES intervention, and improvements in functional mobility and QOL were observed. Telerehabilitation to monitor FES may improve access and reduce patient burden; therefore, studying its efficacy is warranted.
摘要：
背景：多发性硬化症（MS）患者的脚下降通常会导致活动性和生活质量（QOL）下降。腓骨神经的功能性电刺激（FES）可以改善足下垂患者的步态，然而，各种障碍限制了广泛的使用。本病例系列的目的是检查远程康复监测的FES设备的可行性，并报告中度MS相关残疾患者的功能移动性和生活质量的变化。
方法：通过3次远程康复治疗，FES的使用在8周内进行。通过完成的远程康复访问百分比和参与者报告的满意度来评估远程康复的可行性。在基线和研究完成时，通过定时25英尺步行（T25FW）评估有和没有FES的功能移动性，定时和去（TUG），和2分钟步行测试（2MWT），多发性硬化影响量表（MSIS-29），和12项多发性硬化步行量表（MSWS-12）。在干预前后，通过改良的疲劳影响量表（MFIS）评估疲劳。
结果：11名参与者（平均年龄=50.4岁[SD10.8]；2名男性）完成了研究。所有（33/33）远程康复访视均已完成，参与者满意度较高，无不良事件。在8周的时候,与基线相比，T25FW有临床意义的改善，2MWT,和TUG为45%，55%,82%的参与者，分别。MSIS-29和MSWS-12的临床上有意义的改善也记录了64%和36%的参与者。分别。
结论：远程康复对于FES干预是安全可行的，并观察到功能移动性和生活质量的改善。监测FES的远程康复可能会改善访问并减轻患者负担；因此，研究其功效是有必要的。
方法：通过3次远程康复治疗，FES的使用在8周内进行。通过完成的远程康复访问百分比和参与者报告的满意度来评估远程康复的可行性。在基线和研究完成时，通过定时25英尺步行（T25FW）评估有和没有FES的功能移动性，定时和去（TUG），和2分钟步行测试（2MWT），多发性硬化影响量表（MSIS-29），和12项多发性硬化步行量表（MSWS-12）。在干预前后，通过改良的疲劳影响量表（MFIS）评估疲劳。
结果：11名参与者（平均年龄=50.4岁[SD10.8]；2名男性）完成了研究。所有（33/33）远程康复访视均已完成，参与者满意度较高，无不良事件。在8周的时候,与基线相比，T25FW有临床意义的改善，2MWT,和TUG为45%，55%,82%的参与者，分别。MSIS-29和MSWS-12的临床上有意义的改善也记录了64%和36%的参与者。分别。
结论：远程康复对于FES干预是安全可行的，并观察到功能移动性和生活质量的改善。监测FES的远程康复可能会改善访问并减轻患者负担；因此，研究其功效是有必要的。
