CONCLUSIONS: This review introduces the molecular characteristics of the YTH domain protein family and their physiological and pathological roles in biological behavior, emphasizing their mechanisms in regulating immune responses and antitumor immunity. Additionally, the review discusses the roles of the YTH domain protein family in immune-related diseases and tumor resistance, highlighting that abnormal expression or dysfunction of YTH proteins is closely linked to tumor resistance.
CONCLUSIONS: This review provides an in-depth understanding of the YTH domain protein family in immune regulation and antitumor immunity, suggesting new strategies and directions for immunotherapy of related diseases. These insights not only deepen our comprehension of m6A modifications and YTH protein functions but also pave the way for future research and clinical applications.
结论:本文介绍了YTH结构域蛋白家族的分子特征及其在生物学行为中的生理病理作用。强调其调节免疫反应和抗肿瘤免疫的机制。此外,这篇综述讨论了YTH结构域蛋白家族在免疫相关疾病和肿瘤耐药中的作用,强调YTH蛋白的异常表达或功能障碍与肿瘤耐药密切相关。
结论:这篇综述为YTH结构域蛋白家族在免疫调节和抗肿瘤免疫中的作用提供了深入的了解,为相关疾病的免疫治疗提供新的策略和方向。这些见解不仅加深了我们对m6A修饰和YTH蛋白功能的理解,而且为未来的研究和临床应用铺平了道路。