Abstract：
Hangeshashinto is a traditional Japanese herbal medicine that is widely recognized for its efficacy in relieving mucositis induced by chemotherapy and radiotherapy. We herein present the cases of two patients with head and neck cancer who were clinically diagnosed with severe drug-induced interstitial lung disease (DILD) following Hangeshashinto administration for radiation-induced mucositis. Although Hangeshashinto has beneficial properties, it is also associated with a relatively low incidence of DILD, including some reports of death. To ensure patient safety, greater attention should be paid when prescribing Hangeshashinto, especially for elderly patients with factors predisposing them to develop severe DILD.
摘要：
Hangeshashinto是一种传统的日本草药，因其在缓解化疗和放疗引起的粘膜炎方面的功效而被广泛认可。我们在此介绍了两名头颈癌患者的病例，这些患者在接受Hangeshashinto治疗放射性粘膜炎后被临床诊断为严重的药物诱发的间质性肺病（DILD）。尽管Hangeshashinto具有有益的特性，它还与相对较低的DILD发病率有关，包括一些死亡报告.为了确保患者安全，在开恒河通时应该更加注意，特别是对于有因素的老年患者，他们会发展为严重的DILD。
