Abstract：
Sarcoidosis is a systemic inflammatory disease of unknown origin, which consists of the formation of multiple sterile noncaseating granulomas. Inhaled antigens are believed to initiate disease in prone individuals, considering that almost all patients present pulmonary or mediastinal lymph node disease. Extrapulmonary manifestations are common and diverse: practically any organ system can be affected, and treatment can range from simple watchful waiting to intense immunosuppression. In this article, we review current concepts about sarcoidosis in an overview, focusing on recognition and treatment of its major clinical phenotypes.
摘要：
结节病是一种不明原因的全身性炎症性疾病，由多个无菌的非干酪性肉芽肿的形成组成。吸入的抗原被认为在易感个体中引发疾病，考虑到几乎所有患者都存在肺或纵隔淋巴结疾病。肺外表现是常见且多样的：几乎任何器官系统都可能受到影响，治疗可以从简单的观察等待到强烈的免疫抑制。在这篇文章中,我们在概述中回顾了当前关于结节病的概念，重点识别和治疗其主要临床表型。
