PDF(Pubmed)
Abstract：
BACKGROUND: Mothers play a crucial role in influencing their daughters\' HPV vaccination decisions. Addressing barriers to receiving HPV vaccination among mothers of girls may achieve two goals in one strike: increasing vaccination coverage among both mothers and their daughters. This study aims to examine the HPV vaccination uptake and its determinants among mothers of girls in China at both the individual and interpersonal levels.
METHODS: From July to October 2023, a cross-sectional online study was conducted to investigate HPV vaccine refusal for daughters aged 9-17 years among 11,678 mothers in Shenzhen, China. A randomized selection method was employed, targeting 11 primary schools and 13 secondary schools in Shenzhen. The research team invited mothers of girls to participate in an anonymous online survey. Multilevel logistic regression models (level 1: schools; level 2: individual participants) were employed to analyze the data.
RESULTS: Among 11,678 mothers, 41.1% self-reported receiving at least one dose of HPV vaccination. Through multilevel logistic regression analysis, eight items measuring illness representations of HPV, which refers to how people think about HPV, were associated with higher HPV vaccination uptake (AOR: 1.02-1.14). These items included identity (identifying symptoms of HPV), timeline (whether HPV is acute/chronic), negative consequences, personal and treatment control (whether HPV is under volitional control), concern, negative emotions, and coherence (overall understanding of HPV). In addition, participants refusing HPV vaccines for the index daughters (AOR: 0.82, 95%CI: 0.76, 0.89) had lower vaccine uptake. Perceived more difficulties in accessing the 9-valent vaccines (AOR: 1.06, 95%CI: 1.04, 1.08) and more satisfaction with vaccine-related promotional materials (AOR: 1.50, 95%CI: 1.46, 1.54) at the individual level were associated with higher vaccine uptake. At the interpersonal factors, higher frequency of exposure to testimonials given by others about HPV vaccination on social media (AOR: 1.19, 95%CI: 1.14, 1.25) and thoughtful consideration of the veracity of the information (AOR: 1.11, 95%CI: 1.07, 1.16) were correlated with higher HPV vaccination uptake.
CONCLUSIONS: These findings offer essential implications for modifying HPV disease perceptions, addressing difficulties in accessing the 9-valent HPV vaccines, and enhancing health communication needs to improve HPV vaccine uptake among mothers of girls.
METHODS: From July to October 2023, a cross-sectional online study was conducted to investigate HPV vaccine refusal for daughters aged 9-17 years among 11,678 mothers in Shenzhen, China. A randomized selection method was employed, targeting 11 primary schools and 13 secondary schools in Shenzhen. The research team invited mothers of girls to participate in an anonymous online survey. Multilevel logistic regression models (level 1: schools; level 2: individual participants) were employed to analyze the data.
RESULTS: Among 11,678 mothers, 41.1% self-reported receiving at least one dose of HPV vaccination. Through multilevel logistic regression analysis, eight items measuring illness representations of HPV, which refers to how people think about HPV, were associated with higher HPV vaccination uptake (AOR: 1.02-1.14). These items included identity (identifying symptoms of HPV), timeline (whether HPV is acute/chronic), negative consequences, personal and treatment control (whether HPV is under volitional control), concern, negative emotions, and coherence (overall understanding of HPV). In addition, participants refusing HPV vaccines for the index daughters (AOR: 0.82, 95%CI: 0.76, 0.89) had lower vaccine uptake. Perceived more difficulties in accessing the 9-valent vaccines (AOR: 1.06, 95%CI: 1.04, 1.08) and more satisfaction with vaccine-related promotional materials (AOR: 1.50, 95%CI: 1.46, 1.54) at the individual level were associated with higher vaccine uptake. At the interpersonal factors, higher frequency of exposure to testimonials given by others about HPV vaccination on social media (AOR: 1.19, 95%CI: 1.14, 1.25) and thoughtful consideration of the veracity of the information (AOR: 1.11, 95%CI: 1.07, 1.16) were correlated with higher HPV vaccination uptake.
CONCLUSIONS: These findings offer essential implications for modifying HPV disease perceptions, addressing difficulties in accessing the 9-valent HPV vaccines, and enhancing health communication needs to improve HPV vaccine uptake among mothers of girls.
摘要：
背景：母亲在影响其女儿的HPV疫苗接种决策方面发挥着至关重要的作用。解决女孩母亲接受HPV疫苗接种的障碍可能会在一次罢工中实现两个目标：增加母亲及其女儿的疫苗接种覆盖率。这项研究旨在从个人和人际层面检查中国女孩母亲的HPV疫苗接种率及其决定因素。
方法：2023年7月至10月，在深圳11,678名母亲中进行了一项横断面在线研究，以调查9-17岁的女儿对HPV疫苗的拒绝。中国。采用随机选择方法，针对深圳11所小学和13所中学。研究小组邀请女孩的母亲参加匿名在线调查。采用多水平逻辑回归模型（1级：学校；2级：个体参与者）分析数据。
结果：在11,678名母亲中，41.1％的自我报告接受至少一剂HPV疫苗接种。通过多水平Logistic回归分析,八个项目测量HPV的疾病表征，指的是人们对HPV的看法，与较高的HPV疫苗接种率相关（AOR：1.02-1.14）。这些项目包括身份（识别HPV的症状），时间表（HPV是否为急性/慢性），负面后果,个人和治疗控制（HPV是否在自愿控制下），关注,负面情绪,和连贯性（对HPV的整体理解）。此外,拒绝为索引子代接种HPV疫苗的参与者(AOR:0.82,95CI:0.76,0.89)的疫苗接种率较低.在个人水平上，获得9价疫苗（AOR：1.06，95CI：1.04，1.08）的难度更大，对疫苗相关宣传材料的满意度更高（AOR：1.50，95CI：1.46，1.54）与更高的疫苗摄取相关。在人际关系因素上，在社交媒体上接触其他人提供的HPV疫苗接种证明的频率较高(AOR:1.19,95CI:1.14,1.25)以及对信息真实性的深思熟虑考虑(AOR:1.11,95CI:1.07,1.16)与较高的HPV疫苗接种率相关.
结论：这些发现为改变HPV疾病的认知提供了重要的意义。解决获得9价HPV疫苗的困难，和加强健康沟通需要提高HPV疫苗的吸收在母亲的女孩。
方法：2023年7月至10月，在深圳11,678名母亲中进行了一项横断面在线研究，以调查9-17岁的女儿对HPV疫苗的拒绝。中国。采用随机选择方法，针对深圳11所小学和13所中学。研究小组邀请女孩的母亲参加匿名在线调查。采用多水平逻辑回归模型（1级：学校；2级：个体参与者）分析数据。
结果：在11,678名母亲中，41.1％的自我报告接受至少一剂HPV疫苗接种。通过多水平Logistic回归分析,八个项目测量HPV的疾病表征，指的是人们对HPV的看法，与较高的HPV疫苗接种率相关（AOR：1.02-1.14）。这些项目包括身份（识别HPV的症状），时间表（HPV是否为急性/慢性），负面后果,个人和治疗控制（HPV是否在自愿控制下），关注,负面情绪,和连贯性（对HPV的整体理解）。此外,拒绝为索引子代接种HPV疫苗的参与者(AOR:0.82,95CI:0.76,0.89)的疫苗接种率较低.在个人水平上，获得9价疫苗（AOR：1.06，95CI：1.04，1.08）的难度更大，对疫苗相关宣传材料的满意度更高（AOR：1.50，95CI：1.46，1.54）与更高的疫苗摄取相关。在人际关系因素上，在社交媒体上接触其他人提供的HPV疫苗接种证明的频率较高(AOR:1.19,95CI:1.14,1.25)以及对信息真实性的深思熟虑考虑(AOR:1.11,95CI:1.07,1.16)与较高的HPV疫苗接种率相关.
结论：这些发现为改变HPV疾病的认知提供了重要的意义。解决获得9价HPV疫苗的困难，和加强健康沟通需要提高HPV疫苗的吸收在母亲的女孩。
