Mesh : Phantoms, Imaging Cortical Bone / diagnostic imaging physiology Ultrasonography / methods instrumentation Fourier Analysis Ultrasonic Waves Humans Transducers Numerical Analysis, Computer-Assisted Computer Simulation

来  源:   DOI:10.1121/10.0028173

Abstract:
Over the past few decades, early osteoporosis detection using ultrasonic bone quality evaluation has gained prominence. Specifically, various studies focused on axial transmission using ultrasonic guided waves and have highlighted this technique\'s sensitivity to intrinsic properties of long cortical bones. This work aims to demonstrate the potential of low-frequency ultrasonic guided waves to infer the properties of the bone inside which they are propagating. A proprietary ultrasonic transducer, tailored to transmit ultrasonic guided waves under 500 kHz, was used for the data collection. The gathered data underwent two-dimensional fast Fourier transform processing to extract experimental dispersion curves. The proposed inversion scheme compares experimental dispersion curves with simulated dispersion curves calculated through the semi-analytical iso-geometric analysis (SAIGA) method. The numerical model integrates a bone phantom plate coupled with a soft tissue layer on its top surface, mimicking the experimental bone phantom plates. Subsequently, the mechanical properties of the bone phantom plates were estimated by reducing the misfit between the experimental and simulated dispersion curves. This inversion leaned heavily on the dispersive trajectories and amplitudes of ultrasonic guided wave modes. Results indicate a marginal discrepancy under 5% between the mechanical properties ascertained using the SAIGA-based inversion and those measured using bulk wave pulse-echo measurements.
摘要:
在过去的几十年里,使用超声骨质量评估进行早期骨质疏松检测已得到重视。具体来说,各种研究集中在使用超声导波的轴向传输,并强调了这种技术对长皮质骨的内在特性的敏感性。这项工作旨在证明低频超声导波的潜力,以推断它们在其中传播的骨骼的特性。专有的超声波换能器,适合在500kHz以下发射超声导波,用于数据收集。收集的数据经过二维快速傅里叶变换处理,以提取实验色散曲线。所提出的反演方案将实验色散曲线与通过半解析等几何分析(SAIGA)方法计算的模拟色散曲线进行了比较。数值模型集成了一个骨模板,其顶部表面上有一个软组织层,模仿实验骨模板。随后,通过减少实验和模拟色散曲线之间的失配来估计骨模型板的机械性能。这种反演严重依赖于超声导波模式的色散轨迹和振幅。结果表明,使用基于SAIGA的反演确定的机械性能与使用体波脉冲回波测量测得的机械性能之间存在5%以下的边际差异。
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