Abstract：
BACKGROUND: Pre-vascular facial nodes (PV-FNs; perifacial lymph nodes) are supra-mandibular lymph nodes above the inferior border of the mandible. These are not part of routine neck dissection done for OCSCC. These lymph nodes can be sentinel station for metastatic lymph nodes from gingivobuccal complex cancers and are missed during routine neck dissection. It is imperative to include this sentinel station in routine neck dissection to prevent nodal recurrences.
METHODS: One hundred thirty-seven patients with GBCC (T1-T4) were prospectively recruited between May 2020 and June 2022 with the intent to evaluate the incidence of PV-FN metastases and clinicopathological factors predicting them.
RESULTS: PV-FN metastases were seen in 26 patients (18.9%; 26/137). The occult metastasis rate was 8.7% (12/137). On multivariate analysis, pathological T4 stage (pT4), LVE positivity, and intermediate-high BGS were statistically significant predictors of PV-FN metastases in our study.
CONCLUSIONS: Incidence of PV-FN metastasis is high (18.9%) in GBCC, which can be potentially the first sentinel station in the lymphatic drainage pattern for this sub-site. Meticulous clearance of this nodal basin is of paramount importance during neck dissection to prevent nodal recurrences.
METHODS: Level 2 (CEBM-Level of Evidence-2.1) Laryngoscope, 2024.
METHODS: One hundred thirty-seven patients with GBCC (T1-T4) were prospectively recruited between May 2020 and June 2022 with the intent to evaluate the incidence of PV-FN metastases and clinicopathological factors predicting them.
RESULTS: PV-FN metastases were seen in 26 patients (18.9%; 26/137). The occult metastasis rate was 8.7% (12/137). On multivariate analysis, pathological T4 stage (pT4), LVE positivity, and intermediate-high BGS were statistically significant predictors of PV-FN metastases in our study.
CONCLUSIONS: Incidence of PV-FN metastasis is high (18.9%) in GBCC, which can be potentially the first sentinel station in the lymphatic drainage pattern for this sub-site. Meticulous clearance of this nodal basin is of paramount importance during neck dissection to prevent nodal recurrences.
METHODS: Level 2 (CEBM-Level of Evidence-2.1) Laryngoscope, 2024.
摘要：
背景：血管前面部淋巴结（PV-FN；面周淋巴结）是下颌骨下缘上方的下颌上淋巴结。这些不是OCSCC常规颈清扫术的一部分。这些淋巴结可以是来自牙龈颊复合体癌的转移性淋巴结的前哨站，并且在常规颈部清扫术中被遗漏。必须在常规颈淋巴结清扫术中包括此前哨站，以防止淋巴结复发。
方法：2020年5月至2022年6月，前瞻性招募了137例GBCC（T1-T4）患者，旨在评估PV-FN转移的发生率和预测其临床病理因素。
结果：在26例患者中发现了PV-FN转移（18.9％；26/137）。隐匿性转移率为8.7%(12/137)。在多变量分析中，病理T4分期（pT4），LVE积极性,在我们的研究中，中高BGS是PV-FN转移的统计学显著预测因子。
结论：GBCC中PV-FN转移的发生率很高（18.9%），这可能是该子站点淋巴引流模式中的第一个前哨站。在颈淋巴结清扫术中，要防止淋巴结复发，必须仔细清除该淋巴结盆地。
方法：2级（CEBM-证据级别-2.1）喉镜，2024.
方法：2020年5月至2022年6月，前瞻性招募了137例GBCC（T1-T4）患者，旨在评估PV-FN转移的发生率和预测其临床病理因素。
结果：在26例患者中发现了PV-FN转移（18.9％；26/137）。隐匿性转移率为8.7%(12/137)。在多变量分析中，病理T4分期（pT4），LVE积极性,在我们的研究中，中高BGS是PV-FN转移的统计学显著预测因子。
结论：GBCC中PV-FN转移的发生率很高（18.9%），这可能是该子站点淋巴引流模式中的第一个前哨站。在颈淋巴结清扫术中，要防止淋巴结复发，必须仔细清除该淋巴结盆地。
方法：2级（CEBM-证据级别-2.1）喉镜，2024.
