PDF(Pubmed)
Abstract：
UNASSIGNED: Covered stents are used during congenital cardiac interventions to treat stenotic or injured vessels or to exclude unwanted vascular connections. The ability to postdilate a stented vessel to keep pace with somatic growth is critical in children. In this study, we aimed to compare in vitro performance of 2 brands of covered stents during serial dilations to demonstrate the threshold for stent fracture and polytetrafluoroethylene tear and define recoil and foreshortening characteristics.
UNASSIGNED: iCast and VBX stents of various sizes were measured before and after expansion and through serial dilations. Dilations were performed at 2-mm increments until stent fracture, polytetrafluoroethylene tear, and \"napkin-ring\" formation, to a maximum of 22-mm diameter.
UNASSIGNED: The 5- and 6-mm VBX stents fractured during dilation with 10-mm balloon; the 7-mm VBX stents fractured on the 14-mm balloon; and the largest VBX stents fractured on the 20- or 22-mm balloons. iCast stents experienced partial fracture during dilation with the 14- or 16-mm balloons and complete fracture past dilation with 16-mm balloons. VBX stents recoiled less at nominal diameters. Both stents had similar foreshortening at nominal diameters, although VBX stents had more significant foreshortening with postdilation.
UNASSIGNED: All iCast stents experienced partial fracture with dilation between 14- and 16-mm diameter and had unpredictable fracturing patterns. VBX stents showed a more predictable fracture pattern and had less recoil with nominal inflation but more foreshortening with postdilation. These findings may add clinical benefit and empower physicians to make optimal decisions regarding future planning of interventions in children with congenital heart disease.
UNASSIGNED: iCast and VBX stents of various sizes were measured before and after expansion and through serial dilations. Dilations were performed at 2-mm increments until stent fracture, polytetrafluoroethylene tear, and \"napkin-ring\" formation, to a maximum of 22-mm diameter.
UNASSIGNED: The 5- and 6-mm VBX stents fractured during dilation with 10-mm balloon; the 7-mm VBX stents fractured on the 14-mm balloon; and the largest VBX stents fractured on the 20- or 22-mm balloons. iCast stents experienced partial fracture during dilation with the 14- or 16-mm balloons and complete fracture past dilation with 16-mm balloons. VBX stents recoiled less at nominal diameters. Both stents had similar foreshortening at nominal diameters, although VBX stents had more significant foreshortening with postdilation.
UNASSIGNED: All iCast stents experienced partial fracture with dilation between 14- and 16-mm diameter and had unpredictable fracturing patterns. VBX stents showed a more predictable fracture pattern and had less recoil with nominal inflation but more foreshortening with postdilation. These findings may add clinical benefit and empower physicians to make optimal decisions regarding future planning of interventions in children with congenital heart disease.
摘要：
■覆膜支架在先天性心脏介入治疗期间用于治疗狭窄或损伤的血管或排除不需要的血管连接。在儿童中，对支架血管进行后扩张以跟上躯体生长的能力至关重要。在这项研究中,我们的目的是比较2个品牌的覆膜支架在连续扩张过程中的体外性能，以证明支架骨折和聚四氟乙烯撕裂的阈值，并定义反冲和缩短特征。
■在扩张前后以及通过连续扩张测量各种尺寸的iCast和VBX支架。以2mm的增量进行扩张直至支架断裂,聚四氟乙烯撕裂，和“餐巾环”阵型，最大直径为22毫米。
■5毫米和6毫米VBX支架在用10毫米球囊扩张时断裂；7毫米VBX支架在14毫米球囊上断裂；最大的VBX支架在20或22毫米球囊上断裂。在使用14-或16-mm球囊扩张期间,铸造支架经历部分骨折,并且在使用16-mm球囊扩张之后经历完全骨折。VBX支架在公称直径时反冲较小。两种支架在标称直径处具有相似的缩短,尽管VBX支架在扩张后有更显著的缩短。
■所有iCast支架都经历了部分骨折，直径在14至16mm之间扩张，并且具有不可预测的断裂模式。VBX支架显示出更可预测的断裂模式，并且在名义充气时后坐力较小，但在扩张后时缩短更多。这些发现可能会增加临床益处，并使医生能够就先天性心脏病儿童的未来干预计划做出最佳决策。
■在扩张前后以及通过连续扩张测量各种尺寸的iCast和VBX支架。以2mm的增量进行扩张直至支架断裂,聚四氟乙烯撕裂，和“餐巾环”阵型，最大直径为22毫米。
■5毫米和6毫米VBX支架在用10毫米球囊扩张时断裂；7毫米VBX支架在14毫米球囊上断裂；最大的VBX支架在20或22毫米球囊上断裂。在使用14-或16-mm球囊扩张期间,铸造支架经历部分骨折,并且在使用16-mm球囊扩张之后经历完全骨折。VBX支架在公称直径时反冲较小。两种支架在标称直径处具有相似的缩短,尽管VBX支架在扩张后有更显著的缩短。
■所有iCast支架都经历了部分骨折，直径在14至16mm之间扩张，并且具有不可预测的断裂模式。VBX支架显示出更可预测的断裂模式，并且在名义充气时后坐力较小，但在扩张后时缩短更多。这些发现可能会增加临床益处，并使医生能够就先天性心脏病儿童的未来干预计划做出最佳决策。
