PDF(Pubmed)
Abstract：
UNASSIGNED: Patent ductus arteriosus (PDA) stent placement and systemic-pulmonary surgical shunt procedure can both be performed as palliation for infants with duct-dependent pulmonary circulation. The aim of this meta-analysis and literature review was to compare outcomes and study populations between the 2 methods as well as review the technical considerations and complications of PDA stenting.
UNASSIGNED: A systematic search was conducted using the PubMed database and meta-analysis was performed. Risk ratio and mean difference were used to compare the reported outcomes of studies across patients receiving PDA stent and surgical shunt.
UNASSIGNED: In total, 1094 patients from 8 comparative observational studies were included. The PDA stent group had a lower mortality rate and a shorter hospital length of stay than the systemic-pulmonary surgical shunt group, although at the expense of increased reintervention rates. There were higher proportions of patients with single-ventricle physiology and single-source pulmonary blood flow in the surgical shunt group.
UNASSIGNED: PDA stenting appears to be a noninferior or possibly superior method of palliation for duct-dependent pulmonary circulation compared with systemic-pulmonary surgical shunt, recognizing, however, that patients receiving surgical shunt more often had single-ventricle physiology or single-source pulmonary blood flow in this meta-analysis.
UNASSIGNED: A systematic search was conducted using the PubMed database and meta-analysis was performed. Risk ratio and mean difference were used to compare the reported outcomes of studies across patients receiving PDA stent and surgical shunt.
UNASSIGNED: In total, 1094 patients from 8 comparative observational studies were included. The PDA stent group had a lower mortality rate and a shorter hospital length of stay than the systemic-pulmonary surgical shunt group, although at the expense of increased reintervention rates. There were higher proportions of patients with single-ventricle physiology and single-source pulmonary blood flow in the surgical shunt group.
UNASSIGNED: PDA stenting appears to be a noninferior or possibly superior method of palliation for duct-dependent pulmonary circulation compared with systemic-pulmonary surgical shunt, recognizing, however, that patients receiving surgical shunt more often had single-ventricle physiology or single-source pulmonary blood flow in this meta-analysis.
摘要：
■动脉导管未闭（PDA）支架置入术和体肺外科分流术均可用于缓解患有导管依赖性肺循环的婴儿。本荟萃分析和文献综述的目的是比较两种方法的结局和研究人群，并回顾PDA支架置入术的技术考虑和并发症。
■使用PubMed数据库进行系统搜索并进行荟萃分析。使用风险比和平均差异来比较接受PDA支架和手术分流的患者的研究报告结果。
■总共，纳入了来自8项比较观察性研究的1094名患者。PDA支架组比体肺分流术组有更低的死亡率和更短的住院时间。尽管以提高再干预率为代价。在手术分流组中，单心室生理和单源肺血流的患者比例更高。
■与体肺外科分流术相比，PDA支架置入术对导管依赖性肺循环的缓解方法似乎不逊色或可能更优，承认，然而,在这项荟萃分析中,接受手术分流术的患者更经常出现单心室生理或单源肺血流.
■使用PubMed数据库进行系统搜索并进行荟萃分析。使用风险比和平均差异来比较接受PDA支架和手术分流的患者的研究报告结果。
■总共，纳入了来自8项比较观察性研究的1094名患者。PDA支架组比体肺分流术组有更低的死亡率和更短的住院时间。尽管以提高再干预率为代价。在手术分流组中，单心室生理和单源肺血流的患者比例更高。
■与体肺外科分流术相比，PDA支架置入术对导管依赖性肺循环的缓解方法似乎不逊色或可能更优，承认，然而,在这项荟萃分析中,接受手术分流术的患者更经常出现单心室生理或单源肺血流.
